Difference between revisions of "Os02g0214900"

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The rice '''Os02g0214900''' was reported as '''HDA703''' in 2009 <ref name="ref1" /> by researchers from the China.  
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The rice '''''Os02g0214900''''' was reported as '''''OsHDAC3''''' in 2002 <ref name="ref1" /> by researchers from Korea.  
 
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==Annotated Information==
 
==Annotated Information==
[[File:30-f1.png |right |thumb |10000px |''''''Fig. 1. Expression analysis of the rice HDAC genes.'''''']]
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===Gene Symbol===
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*'''''Os02g0214900''''' '''''<=>''''' '''''OsHDAC3''''','''''HDAC3'''''
 
===Function===
 
===Function===
*rice HDAC genes may have divergent developmental functions  
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* Histone deacetylases (HDACs) modulate chromatin structure and transcription.
<br>
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* HDACs have been studied as negative regulators in eukaryotic transcription.
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* The '''''OsHDAC1''''' gene encoded a protein of approximately 57 kDa that shared 73.5%, 72.7%, 79.9%, and 57.1% amino acid sequence identity with the '''''OsHDAC2, OsHDAC3''''', maize '''''RPD3''''', and human '''''HDAC1''''' proteins, respectively.
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* '''''OsHDAC1''''' functions in the genome-wide programming of gene expression.
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===Expression===
 
===Expression===
*Down-regulation of HDA703 by amiRNA reduced rice peduncle elongation and fertility, while inactivation of a closely related homolog HDA710 by RNAi affected vegetative growth.  
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* '''''OsHDAC1''''' was expressed at similar levels in the leaves, roots, and callus cells, whereas '''''OsHDAC2''''' and '''''OsHDAC3''''' were expressed in the roots and callus cells, but not in the leaves, exhibiting distinct tissue specificity.  
*HDA704 RNAi altered plant height and flag leaf morphology. Down-regulation of HDT702 led to the production of narrowed leaves and stems.  
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===Evolution===
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* Genomic structures and Southern blot analyses revealed that '''''OsHDAC1''''', '''''OsHDAC2''''', '''''OsHDAC3''''' contained seven, six, and seven exons, respectively, and constituted a class I-type family in the rice genome.  
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==Labs working on this gene==
 
==Labs working on this gene==
*National Key Laboratory for Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China
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* Department of Biological Science, Myongji University, Yongin 449-728, Korea, and
*Institut de Biotechnologie des Plantes, Université Paris sud 11, 91405 Orsay, France
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* Department of Bioscience and Biotechnology, Sejong University, Seoul 143-747, Korea
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==References==
 
==References==
 
<references>
 
<references>
<ref name="ref1">
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* <ref name="ref1">
R. Pandey, A. Muller, C.A. Napoli, D.A. Selinger, C.S. Pikaard, E.J. Richards,J. Bender, D.W. Mount, R.A. Jorgensen, Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes, Nucleic Acids Res. 30 (2002) 5036–5055.
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Jang IC, Pahk YM, Song SI, Kwon HJ, Nahm BH, Kim JK. Structure and expression
</ref>
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of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1
 
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overexpression in transgenic plants leads to increased growth rate and altered
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architecture. Plant J. 2003 Feb;33(3):531-41. PubMed PMID: 12581311.</ref>
 
</references>
 
</references>
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==Structured Information==
 
==Structured Information==
 
     [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 2]]
 
     [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 2]]

Latest revision as of 07:59, 3 March 2017

The rice Os02g0214900 was reported as OsHDAC3 in 2002 [1] by researchers from Korea.

Annotated Information

Gene Symbol

  • Os02g0214900 <=> OsHDAC3,HDAC3

Function

  • Histone deacetylases (HDACs) modulate chromatin structure and transcription.
  • HDACs have been studied as negative regulators in eukaryotic transcription.
  • The OsHDAC1 gene encoded a protein of approximately 57 kDa that shared 73.5%, 72.7%, 79.9%, and 57.1% amino acid sequence identity with the OsHDAC2, OsHDAC3, maize RPD3, and human HDAC1 proteins, respectively.
  • OsHDAC1 functions in the genome-wide programming of gene expression.

Expression

  • OsHDAC1 was expressed at similar levels in the leaves, roots, and callus cells, whereas OsHDAC2 and OsHDAC3 were expressed in the roots and callus cells, but not in the leaves, exhibiting distinct tissue specificity.

Evolution

  • Genomic structures and Southern blot analyses revealed that OsHDAC1, OsHDAC2, OsHDAC3 contained seven, six, and seven exons, respectively, and constituted a class I-type family in the rice genome.

Labs working on this gene

  • Department of Biological Science, Myongji University, Yongin 449-728, Korea, and
  • Department of Bioscience and Biotechnology, Sejong University, Seoul 143-747, Korea

References

  1. Jang IC, Pahk YM, Song SI, Kwon HJ, Nahm BH, Kim JK. Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture. Plant J. 2003 Feb;33(3):531-41. PubMed PMID: 12581311.

Structured Information