Difference between revisions of "Os01g0233500"
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==Annotated Information== | ==Annotated Information== | ||
| + | ===Gene Symbol=== | ||
| + | *'''''Os01g0233500''''' '''''<=>''''' '''''Orysa;CycA1;1''''' | ||
===Function=== | ===Function=== | ||
* Cyclins, the known activators for activity of CDKs, play crucial roles for cell cycle progression in eukaryotes.<ref name="ref1" /><ref name="ref2" /> | * Cyclins, the known activators for activity of CDKs, play crucial roles for cell cycle progression in eukaryotes.<ref name="ref1" /><ref name="ref2" /> | ||
Latest revision as of 10:16, 28 March 2017
The rice Os01g0233500 was reported as Orysa;CycA1;1 in 2006 [1] by researchers from China.
Contents
Annotated Information
Gene Symbol
- Os01g0233500 <=> Orysa;CycA1;1
Function
- Cyclins, the known activators for activity of CDKs, play crucial roles for cell cycle progression in eukaryotes.[1][2]
- In plants, cyclin binding not only activates CDKs by inducing a configuration alteration at the catalytic sites, but also contributes to the subcellular localization and substrate specificity of the complex as well as regulation of protein stability.[1][2]
Evolution
- Phylogenetic analysis indicated that both Arabidopsis and rice shared eight types of cyclins, A-, B-, D-, H-, L-, SDS-, T- and P-type, whereas C- and J18-type cyclins were specific to Arabidopsis, and F-type cyclins, lacking clear homologues in Arabidopsis, were unique to rice.[1]
Knowledge extension
- Similar to animals and yeasts, cell proliferation in plants is mainly controlled by a family of cyclin-dependent kinases (CDKs). The activity of CDKs is directly regulated by binding and activation of cyclins as well as other mechanisms that consist of protein phosphorylation/ dephosphorylation by specific kinases/phosphatases, proteolysis, CDK inhibitor protein (CKI) binding, etc.
- Cyclins were initially discovered in marine inverte-brates as proteins that accumulated at specific time points of the cell cycle and were subsequently degraded quickly.[1]
You can also add sub-section(s) at will.
Labs working on this gene
- Rice Functional Genomics, Joint Laboratory of Temasek Life Sciences Laboratory of Singapore and Institute of Genetics and Developmental Biology
- Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, 100101 Beijing, China
- Rice Functional Genomics Group, Temasek Life Science Laboratory, 1 Research Link, The National University of Singapore, 117604 Singapore, Singapore
References
- ↑ 1.0 1.1 1.2 1.3 1.4 La H, Li J, Ji Z, Cheng Y, Li X, Jiang S, Venkatesh PN, Ramachandran S. Genome-wide analysis of cyclin family in rice (Oryza Sativa L.). Mol Genet Genomics. 2006 Apr;275(4):374-86. Epub 2006 Jan 25. PubMed PMID: 16435118.
- ↑ 2.0 2.1 Wang G, Kong H, Sun Y, Zhang X, Zhang W, Altman N, DePamphilis CW, Ma H. Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteins. Plant Physiol. 2004 Jun;135(2):1084-99. PubMed PMID: 15208425; PubMed Central PMCID: PMC514142.
