Difference between revisions of "Os04g0429100"

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===Phenotypic analysis===
 
===Phenotypic analysis===
*Compared with the wild-type, SDG708-knockdown rice mutants displayed a late-flowering phenotype under both long-day and short-day conditions because of the down-regulation of the key flowering regulatory genes Heading date 3a (Hd3a), RICE FLOWERING LOCUS T1(RFT1), and Early heading date 1 (Ehd1).
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*Compared with the wild-type, '''''SDG708'''''-knockdown rice mutants displayed a late-flowering phenotype under both long-day and short-day conditions because of the down-regulation of the key flowering regulatory genes Heading date 3a (Hd3a), RICE FLOWERING LOCUS T1(RFT1), and Early heading date 1 (Ehd1).
*Chromatin immunoprecipitation experiments indicated that H3K36me1, H3K36me2, and H3K36me3 levels were reduced at these loci in SDG708-deficient plants.
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*Chromatin immunoprecipitation experiments indicated that H3K36me1, H3K36me2, and H3K36me3 levels were reduced at these loci in '''''SDG708'''''-deficient plants.
 
*Knockdown of '''''SDG708''''' led to misexpression of a set of functional genes and a genome-wide decrease in H3K36me1/2/3 levels during the early growth stages of rice.
 
*Knockdown of '''''SDG708''''' led to misexpression of a set of functional genes and a genome-wide decrease in H3K36me1/2/3 levels during the early growth stages of rice.
  

Latest revision as of 02:38, 26 May 2017

The rice Os04g0429100 was reported as SDG708 in 2015 [1] by researchers from China and France.

Annotated Information

Gene Symbol

  • Os04g0429100 <=> SDG708

Function

SDG708 is a methyltransferase that catalyses genome-wide deposition of all three methyl groups on H3K36 and is involved in many biological processes in addition to flowering promotion.

Phenotypic analysis

  • Compared with the wild-type, SDG708-knockdown rice mutants displayed a late-flowering phenotype under both long-day and short-day conditions because of the down-regulation of the key flowering regulatory genes Heading date 3a (Hd3a), RICE FLOWERING LOCUS T1(RFT1), and Early heading date 1 (Ehd1).
  • Chromatin immunoprecipitation experiments indicated that H3K36me1, H3K36me2, and H3K36me3 levels were reduced at these loci in SDG708-deficient plants.
  • Knockdown of SDG708 led to misexpression of a set of functional genes and a genome-wide decrease in H3K36me1/2/3 levels during the early growth stages of rice.


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Labs working on this gene

  • State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200433,China *State Key Laboratory of Genetics Engineering, MOE Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200433, China
  • CNRS, Institut de Biologie Moleculaire des Plantes, Universite de Strasbourg, Strasbourg, France

References

  1. Liu B, Wei G, Shi J, Jin J, Shen T, Ni T, Shen WH, Yu Y, Dong A. SET DOMAIN GROUP 708, a histone H3 lysine 36-specific methyltransferase, controls flowering time in rice (Oryza sativa). New Phytol. 2016 Apr;210(2):577-88. doi:10.1111/nph.13768. Epub 2015 Dec 7. PubMed PMID: 26639303.

Structured Information