Os07g0409900

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The rice Os07g0409900 was reported as CPK18 in 2014 [1] by researchers from China.

Annotated Information

Gene Symbol

  • Os07g0409900 <=> CPK18,OsCPK18

Function

  • OsCPK18 is a rice (Oryza sativa) calcium-dependent protein kinase (CDPK), it is as an upstream kinase of MAPK (MPK5) in vitro and in vivo.
  • OsCPK18 was shown to phosphorylate and activate MPK5 without affecting the phosphorylation of its TXY motif. Instead, CPK18 was found to predominantly phosphorylate two Thr residues (Thr-14 and Thr-32) that are widely conserved in MAPKs from land plants.
  • Further analyses reveal that the newly identified CPK18-MPK5 pathway represses defense gene expression and negatively regulates rice blast resistance.

Expression

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Evolution

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Labs working on this gene

  • Department of Plant Pathology and Environmental Microbiology, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802

References

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Structured Information

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