IC4R010-miRNA-2010-19796675

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Project Title

  • Identification of novel stress-regulated microRNAs from Oryza sativa L.


The Background of This Project

  • A class of small RNA molecules called microRNAs (miRNAs) has been identified in recent years. MiRNAs are endogenous non-coding

RNAs, are 20–22 nucleotides long, and regulate gene expression in eukaryotes ranging from animals to plants [1–6].

  • Four Dicer-like enzymes (DCL1–DCL4) are encoded in the genome of Arabidopsis thaliana [20]. It has been shown that DCL1 is involved in miRNA accumulation [21]. However, there is no dcl1 mutant available for rice. A recent study has shown that the loss of

function of OsDCL1 transformants could be used to identify miRNAs[22].

Plant Culture & Treatment

Research Findings

Labs working on this Project

  • National Centre for Plant Gene Research, Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences,P.O. Box 2707, South 1-3, Zhongguancun, Beijing 100080, P.R. China
  • State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, P.R. China
  • National Engineering Research Center for Beijing Biochip Technology, Beijing 102206, China


Corresponding Author

  • Fan Chen:fchen@genetics.ac.cn.