Os03g0821300

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Xb15 encodes a PP2C that negatively regulates the XA21-mediated innate immune response.

Annotated Information

Function

  • The rice XA21 protein is representative of the large class of non-RD RKs predicted to be involved in plant innate immunity. XB15 encoded by Xb15 Is an XA21 Binding Protein.

Mutation

  • To explore the role of Xb15 in resistance, the researchers examined whether constitutive overexpression of Xb15 would affect resistance to Xoo. The resulting transgenic plants (NTAP-XB15, pollen donor) were crossed with another Kitaake line possessing an N-terminal Myc-epitope-tagged XA21, under control of its native promoter (Myc-XA21, pollen recipient).

Expression

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Evolution

  • The researchers next compared the PP2C domain of XB15 with other evolutionary related proteins from the reference plant species rice and Arabidopsis, such as Arabidopsis POL and POL-like proteins (PLLs) (Figure 2).
Figure 2. Phylogenetic Relationships among POL and PLL Genes from Rice and Arabidopsis [1].

Labs working on this gene

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References

  1. Park CJ, Peng Y, Chen X, Dardick C, Ruan D, Bart R, Canlas PE, Ronald PC. Rice XB15, a protein phosphatase 2C, negatively regulates cell death and XA21-mediated innate immunity. PLoS Biol. 2008 Sep 23;6(9):e231. doi: 10.1371/journal.pbio.0060231. Erratum in: PLoS Biol. 2008 Nov;6(11):e282. PubMed PMID: 18817453; PubMed Central PMCID: PMC2553837.

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Structured Information