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- 07:44, 8 June 2014 Zhishp (talk | contribs) uploaded File:800px-Nuclear receptor action.png (This figure depicts the mechanism of a class I nuclear receptor (NR) which, in the absence of ligand, is located in the cytosol. Hormone binding triggers dissociation of heat shock proteins (HSP), dimerization, and translocation to the nucleus where it bi)