BIG Search

BIG Search is a scalable text search engine built based on ElasticSearch (a highly scalable open-source full-text search and analytics engine based on Apache Lucene). It features cross-domain search and facilitates users to gain access to a wide range of biomedical data, not only from NGDC databases but also partner databases throughout the world.

e.g., PRJCA000126;SAMC000385;tp53;EGFR; human; KaKs_Calculator

Total 14 record(s) from Ascancer Atlas

as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an EGFR tyrosine kinase inhibitor.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an EGFR tyrosine kinase inhibitor.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
functional_description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
description: Variations in HER1/EGFR pre-mRNA splicing triggered by SRSF2 overexpression in H358 cells resulted, in a drop in HER1/EGFR protein level, which correlated with increased sensitivity to gefitinib, an, EGFR tyrosine kinase inhibitor. AS events for a small number of genes involved in tumor growth and in the response to targeted anticancer therapies.
as_event: Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping
gene_name: EGFR
canonical_transcript_id: EGFR-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=EGFR
as_event: Aberrant Epidermal Growth Factor Receptor RNA Splice Products Are Among the Most Frequent Somatic Alterations in Clear Cell Renal Cell Carcinoma and Are Associated with a Poor Response to Immunotherapy
gene_name: EGFR
canonical_transcript_id: EGFR-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=EGFR
as_event: V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling
functional_description: interact directly or indirectly with CD44 and the EGFR, respectively.
description: interact directly or indirectly with CD44 and the EGFR, respectively.