BIG Search

BIG Search is a scalable text search engine built based on ElasticSearch (a highly scalable open-source full-text search and analytics engine based on Apache Lucene). It features cross-domain search and facilitates users to gain access to a wide range of biomedical data, not only from NGDC databases but also partner databases throughout the world.

e.g., PRJCA000126;SAMC000385;tp53;EGFR; human; KaKs_Calculator

Total 6 record(s) from Ascancer Atlas

as_event: Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline
gene_name: TP53
canonical_transcript_id: TP53-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=TP53
as_event: Identification of a DNA damage–induced alternative splicing pathway that regulates p53 and cellular senescence markers
gene_name: TP53
canonical_transcript_id: TP53-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=TP53
as_event: Influenceofp53IsoformExpressiononSurvivalinHigh-GradeSerousovariancancers
splice_variant_id: TP53-008
gene_name: TP53
canonical_transcript_id: TP53-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=TP53
as_event: Alternativesplicingofp53andp73:thenovelp53splicevariantp53deltaisanindependentprognosticmarkerinovariancancer
splice_variant_id: TP53-005
gene_name: TP53
canonical_transcript_id: TP53-001
url: https://ngdc.cncb.ac.cn/ascancer/search?genename=TP53
as_event: Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia
functional_description: TP53 checkpoint, rendering cells to a more aggressive phenotype as evidenced by proliferation and apoptosis rates.
description: TP53 checkpoint, rendering cells to a more aggressive phenotype as evidenced by proliferation and apoptosis rates.
as_event: Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer
regulatory_gene: TP53