BIG Search

BIG Search is a scalable text search engine built based on ElasticSearch (a highly scalable open-source full-text search and analytics engine based on Apache Lucene). It features cross-domain search and facilitates users to gain access to a wide range of biomedical data, not only from NGDC databases but also partner databases throughout the world.

e.g., PRJCA000126;SAMC000385;tp53;EGFR; human; KaKs_Calculator

Total 63414 record(s) from BioProject

BioProject: The NIH Human Pluripotent Stem Cell Database (Agilent, mRNA)

  • Accession: PRJNA155513
  • Title: The NIH Human Pluripotent Stem Cell Database (Agilent, mRNA)
  • Description: To better understand the extent to which induced pluripotent stem cells (iPSCs) faithfully recapitulate the characteristics of embryonic stem cells (ESCs) under (undiff)erentiated condition, KSR condition and FBS condition and how both compare to somatic tissues under these conditions, we employed whole-genome transcriptome analysis on all twenty one hESC lines available on the pre-2008 NIH Human Pluripotent Stem Cell Registry, eight human iPSCs derived at NIH by retroviral transduction of human fibroblasts and twenty human somatic tissues. One standard culture protocol was used in conjunction with rigorous quality control. Expanded description of methods used and are available at: http://stemcelldb.nih.gov. Overall design: 230 samples: 44 human ESC (UNDIFF), 16 human iPSC (UNDIFF) 44 human ESC (KSR), 15 human iPSC (KSR), 44 human ESC (FBS), 15 human iPSC (FBS), 1 human Brain, 1 human Placenta, 1 human Skeletal Muscle, 1 human Heart, 1 human Liver, 1 human Lung, 1 human Kidney, 1 human Esophagus, 1 human Ovary, 1 human Testes, 1 human Spleen, 1 human Adipose, 1 human Thyroid, 1 human Thymus, 1 human Small Intestine, 1 human Prostate, 1 human Cervix, 1 human Colon, 1 human Bladder, 1 human Trachea) and 32 processing controls (UniRef).
  • BasicInfo : PRJNA155513; Transcriptome or Gene expression; Medical

BioProject: Human ESCs vs Human iPSCs & Human NSCs-ES vs Human NSCs-iPS

  • Accession: PRJNA279508
  • Title: Human ESCs vs Human iPSCs & Human NSCs-ES vs Human NSCs-iPS
  • Description: Transcriptional profiling of Human ESCs vs Human iPSCs, Human NSCs-ES vs Human NSCs-iPS iPSCs generated by using different method, and are not very good at Neural differentiation comapred with Human ESCs Overall design: All adapted in the same culture condition for at least 5 passages; Four-condition experiment; Biological replicates: 2 of each sample
  • BasicInfo : PRJNA279508; Transcriptome or Gene expression; Medical

BioProject: Quantitative transcriptome analysis of human embryonic stem cells, human mesenchymal stem cells and human musculoskeletal stem cells

  • Accession: PRJNA661379
  • Title: Quantitative transcriptome analysis of human embryonic stem cells, human mesenchymal stem cells and human musculoskeletal stem cells
  • Description: We first derived human musculoskeletal stem cells from human embryonic stem cells. mRNA profiles of human embryonic stem cells, human mesenchymal stem cells and human musculoskeletal stem cells were generated by QuantSeq 3’ mRNA-sequencing, in triplicate, using NextSeq 500. Overall design: QuantSeq 3’ mRNA-sequencing of human embryonic stem cells, human mesenchymal stem cells and human musculoskeletal stem cells.
  • BasicInfo : PRJNA661379; Transcriptome or Gene expression; Medical
  • Experiments: SRX9073273 SRX9073271 SRX9073275 SRX9073276 SRX9073274 SRX9073278 more...

BioProject: Single cell RNA sequencing analysis of human embryonic stem cells, human embryoid bodies, human mesenchymal stem cells and human musculoskeletal stem cells

  • Accession: PRJNA662715
  • Title: Single cell RNA sequencing analysis of human embryonic stem cells, human embryoid bodies, human mesenchymal stem cells and human musculoskeletal stem cells
  • Description: NOT PROVIDED; REQUESTED Overall design: We first derived human musculoskeletal stem cells from human embryonic stem cells. Single cell RNA sequencing of human embryonic stem cells, human embryoid bodies, human mesenchymal stem cells and human musculoskeletal stem cells were performed using 10x Genomics Chromium System .
  • BasicInfo : PRJNA662715; Transcriptome or Gene expression; Medical
  • Experiments: SRX9103792 SRX9103793 SRX9103794 SRX9103791

BioProject: human bile metagenome, human gut metagenome Metagenome


BioProject: Human rhinovirus C

  • Accession: PRJNA41899
  • Title: Human rhinovirus C
  • Description: Human rhinovirus C collected from human nasal isolates.
  • BasicInfo : PRJNA41899; Genome sequencing ;

BioProject: Human gut microbiome

  • Accession: PRJEB20174
  • Title: Human gut microbiome
  • Description: Human gut microbiome
  • BasicInfo : PRJEB20174; Other;

BioProject: Characterization of gene expression patterns among human iPS cell-derived cardiomyocytes, iPS cells, fetal human heart tissue and adult human heart tissue

  • Accession: PRJNA646722
  • Title: Characterization of gene expression patterns among human iPS cell-derived cardiomyocytes, iPS cells, fetal human heart tissue and adult human heart tissue
  • Description: Here we provide the gene expression patterns of human iPS cell-derived cardiomyocytes used in the motion field imaging assay, adult human heart tissues, fetal human heart tissue and iPS cells. These data provided the causal relationship between phenotype and function in the human iPS cell-derived cardiomyocytes. Overall design: Comparison of transcriptome profiling among heart tissues and cells including human iPS cell-derived cardiomyocytes, iPS cells, fetal human heart tissue and adult human heart tissue.
  • BasicInfo : PRJNA646722; Transcriptome or Gene expression; Medical
  • Experiments: SRX8748423 SRX8748425 SRX8748422 SRX8748424 SRX8748427 SRX8748428 more...

BioProject: Overexpression of human APOBEC3H in human HEK-293T cells

  • Accession: PRJEB21805
  • Title: Overexpression of human APOBEC3H in human HEK-293T cells
  • Description: To identify transcriptome-wide effects of human APOBEC3H, human HEK-293T cells were transiently transfected with an expression construct for human APOBEC3H ORF cDNA.
  • BasicInfo : PRJEB21805; Other;
  • Experiments: ERX2095671 ERX2095670 ERX2095672

BioProject: Human gene expression altered by Human cytomegalovirus (HCMV) Entry

  • Accession: PRJNA137769
  • Title: Human gene expression altered by Human cytomegalovirus (HCMV) Entry
  • Description: human foreskin fibroblasts were infected with HCMV We monitor cellular gene expression network altered by HCMV entry using Affymetrix Human Genome U133 Plus 2.0 Array Overall design: 2 time points were measured, 5min, 25min
  • BasicInfo : PRJNA137769; Transcriptome or Gene expression; Medical