| URL: | http://www.dkfz.de/en/mga/Groups/LIFEdb-Database.html |
| Full name: | LIFEdb |
| Description: | LIFEdb is desinged to disseminate information on the ORFeome resource (e.g., clone quality metrics) and on the utilization of this resource towards a functional annotation of encoded proteins (genes, subcellular localization data). |
| Year founded: | 2004 |
| Last update: | 2013-01-31 |
| Version: | v1.0 |
| Accessibility: |
Accessible
|
| Country/Region: | Germany |
| Data type: | |
| Data object: |
NA
|
| Database category: | |
| Major species: |
NA
|
| Keywords: |
| University/Institution: | German Cancer Research Center |
| Address: | Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany |
| City: | Heidelberg |
| Province/State: | |
| Country/Region: | Germany |
| Contact name (PI/Team): | Alexander Mehrle |
| Contact email (PI/Helpdesk): | a.mehrle@dkfz.de |
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The LIFEdb database in 2006. [PMID: 16381901]
LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output table and the option to download search results in XML, (iii) the integration of data from cell-based screening assays addressing the influence of protein-overexpression on cell proliferation and (iv) the display of the relative expression ('Electronic Northern') of the genes under investigation using curated gene expression ontology information. LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface. |
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LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system. [PMID: 14681468]
We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on the encoded proteins produced in functional genomics and proteomics approaches. The database also serves as a sample-tracking system to manage the process from cDNA to experimental read-out and data interpretation. A web interface enables the scientific community to explore and visualize features of the annotated cDNAs and ORFs combined with experimental results, and thus helps to unravel new features of proteins with as yet unknown functions. |