| URL: | http://www.sheba-cancer.org.il/e23D |
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| Description: | e23D maps A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism. |
| Year founded: | 2016 |
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| Country/Region: | Israel |
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| University/Institution: | Bar-Ilan University |
| Address: | Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel |
| City: | Ramat-Gan |
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| Country/Region: | Israel |
| Contact name (PI/Team): | Oz Solomon |
| Contact email (PI/Helpdesk): | oz.solomon@live.biu.ac.il |
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e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures. [PMID: 27153640]
e23D, a database of A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures, is presented. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism. |