| URL: | http://www.circbase.org |
| Full name: | circBase |
| Description: | Thousands of circular RNAs (circRNAs) have recently been shown to be expressed in eukaryotic cells [Salzman et al. 2012, Jeck et al. 2013, Memczak et al. 2013, Salzman et al. 2013]. Here you can explore public circRNA datasets and download the custom python scripts needed to discover circRNAs in your own (ribominus) RNA-seq data. New: Sequence-based search Search the database by identifier, gene description, genomic position, or their lists. Retrieve dataset slices by defining a set of conditions (table browser). Export tables in a variety of formats. Export FASTA files containing genomic sequence. Please refer to documentation for further info. |
| Year founded: | 2014 |
| Last update: | July 2017 |
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| Country/Region: | Germany |
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| University/Institution: | Max Delbrück Center for Molecular Medicine |
| Address: | Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany |
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| Country/Region: | Germany |
| Contact name (PI/Team): | Rajewsky N |
| Contact email (PI/Helpdesk): | rajewsky@mdc-berlin.de |
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circBase: a database for circular RNAs. [PMID: 25234927]
Recently, several laboratories have reported thousands of circular RNAs (circRNAs) in animals. Numerous circRNAs are highly stable and have specific spatiotemporal expression patterns. Even though a function for circRNAs is unknown, these features make circRNAs an interesting class of RNAs as possible biomarkers and for further research. We developed a database and website, "circBase," where merged and unified data sets of circRNAs and the evidence supporting their expression can be accessed, downloaded, and browsed within the genomic context. circBase also provides scripts to identify known and novel circRNAs in sequencing data. The database is freely accessible through the web server at http://www.circbase.org/. |