BaAMPs


25760404	BaAMPs: the database of biofilm-active antimicrobial peptides. [PMID: 25760404] Di Luca M, Maccari G, Maisetta G, Batoni G. Abstract Antimicrobial peptides (AMPs) are increasingly being considered as novel agents against biofilms. The development of AMP-based anti-biofilm strategies strongly relies on the design of sequences optimized to target specific features of sessile bacterial/fungal communities. Although several AMP databases have been created and successfully exploited for AMP design, all of these use data collected on peptides tested against planktonic microorganisms. Here, an open-access, manually curated database of AMPs specifically assayed against microbial biofilms (BaAMPs) is presented for the first time. In collecting relevant data from the literature an effort was made to define a minimal standard set of essential information including, for each AMP, the microbial species and biofilm conditions against which it was tested, and the specific assay and peptide concentration used. The availability of these data in an organized framework will benefit anti-biofilm research and support the design of novel molecules active against biofilm. BaAMPs is accessible at http://www.baamps.it. Biofouling. 2015:31(2) \| 76 Citations (from Europe PMC, 2025-03-22)

BaAMPs: the database of biofilm-active antimicrobial peptides. [PMID: 25760404]

Di Luca M, Maccari G, Maisetta G, Batoni G.

Antimicrobial peptides (AMPs) are increasingly being considered as novel agents against biofilms. The development of AMP-based anti-biofilm strategies strongly relies on the design of sequences optimized to target specific features of sessile bacterial/fungal communities. Although several AMP databases have been created and successfully exploited for AMP design, all of these use data collected on peptides tested against planktonic microorganisms. Here, an open-access, manually curated database of AMPs specifically assayed against microbial biofilms (BaAMPs) is presented for the first time. In collecting relevant data from the literature an effort was made to define a minimal standard set of essential information including, for each AMP, the microbial species and biofilm conditions against which it was tested, and the specific assay and peptide concentration used. The availability of these data in an organized framework will benefit anti-biofilm research and support the design of novel molecules active against biofilm. BaAMPs is accessible at http://www.baamps.it.

Biofouling. 2015:31(2) | 76 Citations (from Europe PMC, 2025-03-22)

URL:	http://www.baamps.it
Full name:	biofilm-active AMPs database
Description:	BaAMPs (Biofilm-active AMPs) is a database designed with the key objective of collecting data on AMPs specifically tested against microbial biofilms in an exhaustive and detailed manner. The aim of this project is to provide useful resources for the study of AMPs against biofilms to microbiologist, bioinformatics researcher and medical scientist working in this field in an open-access framework.
Year founded:	2015
Last update:	2017
Version:
Accessibility:	Accessible
Country/Region:	Italy

Data type:	Protein
Data object:	Archaea Bacteria Fungi Virus
Database category:	Literature Metadata Modification
Major species:	Escherichia coli Candida albicans
Keywords:	anti-biofilm compounds antimicrobial peptides medical biofilms web database

University/Institution:	Nanoscience Institute-CNR and SNS
Address:	NEST, Nanoscience Institute-CNR and SNS, Pisa , Italy.
City:	Pisa
Province/State:
Country/Region:	Italy
Contact name (PI/Team):	Mariagrazia Di Luca
Contact email (PI/Helpdesk):	mariagrazia.diluca@nano.cnr.it

Database Commons
a catalog of worldwide biological databases

a catalog of worldwide biological databases

Database Profile

General information

Classification & Tag

Contact information

Publications

Ranking

Community reviews

Word cloud

Tags

Related Databases

Record metadata

Research & Resources

Featured

Alliance & Collaboration

Conference & Outreach

About

Database Commons a catalog of worldwide biological databases