| URL: | http://servers.binf.ku.dk/hemaexplorer |
| Full name: | |
| Description: | HemaExplorer provides a plot of gene expression in hematopoietic cells at different maturation stages based on curated microarray data. |
| Year founded: | 2012 |
| Last update: | NA |
| Version: | v1.0 |
| Accessibility: | |
| Country/Region: | Denmark |
| Data type: | |
| Data object: | |
| Database category: | |
| Major species: | |
| Keywords: |
| University/Institution: | University of Copenhagen |
| Address: | The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark Bioinformatics Centre, Department of Biology, Copenhagen, DK 2200 Denmark |
| City: | Copenhagen |
| Province/State: | |
| Country/Region: | Denmark |
| Contact name (PI/Team): | Bo T. Porse |
| Contact email (PI/Helpdesk): | bo.porse@finsenlab.dk |
|
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis. [PMID: 23143109]
The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover, data from distinct subtypes of human acute myeloid leukemia is included in the database allowing researchers to directly compare gene expression of leukemic cells with those of their closest normal counterpart. Normalization and batch correction lead to full integrity of the data in the database. The HemaExplorer has comprehensive visualization interface that can make it useful as a daily tool for biologists and cancer researchers to assess the expression patterns of genes encountered in research or literature. HemaExplorer is relevant for all research within the fields of leukemia, immunology, cell differentiation and the biology of the haematopoietic system. |
|
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis. [PMID: 22745298]
The HemaExplorer Web server allows for an easy display of mRNA expression profiles for query genes in murine and human hematopoietic stem and progenitor cells that represent consecutive developmental stages along the myeloid differentiation pathway. In addition, it provides the ability to compare gene expression levels in human acute myeloid leukemia (AML) cells with expression levels in normal human hematopoietic stem cells and hematopoietic progenitor cells. The Web server is freely available at http://servers.binf.ku.dk/hemaexplorer/. |