Database Commons
Database Commons

a catalog of worldwide biological databases

Database Profile

General information

URL: https://pophumanscan.uab.cat
Full name:
Description: an online collaborative database that compiles and annotates candidate regions under selection in the human genome.
Year founded: 2019
Last update:
Version:
Accessibility:
Manual:
Accessible
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Country/Region: Spain

Classification & Tag

Data type:
DNA
Data object:
Database category:
Major species:
Keywords:

Contact information

University/Institution: Universitat Autònoma de Barcelona
Address:
City: Barcelona
Province/State:
Country/Region: Spain
Contact name (PI/Team): Sonia Casillas
Contact email (PI/Helpdesk): sonia.casillas@uab.cat

Publications

30335169
PopHumanScan: the online catalog of human genome adaptation. [PMID: 30335169]
Murga-Moreno J, Coronado-Zamora M, Bodelón A, Barbadilla A, Casillas S.

Since the migrations that led humans to colonize Earth, our species has faced frequent adaptive challenges that have left signatures in the landscape of genetic variation and that we can identify in our today's genomes. Here, we (i) perform an outlier approach on eight different population genetic statistics for 22 non-admixed human populations of the Phase III of the 1000 Genomes Project to detect selective sweeps at different historical ages, as well as events of recurrent positive selection in the human lineage; and (ii) create PopHumanScan, an online catalog that compiles and annotates all candidate regions under selection to facilitate their validation and thoroughly analysis. Well-known examples of human genetic adaptation published elsewhere are included in the catalog, as well as hundreds of other attractive candidates that will require further investigation. Designed as a collaborative database, PopHumanScan aims to become a central repository to share information, guide future studies and help advance our understanding of how selection has modeled our genomes as a response to changes in the environment or lifestyle of human populations. PopHumanScan is open and freely available at https://pophumanscan.uab.cat.

Nucleic Acids Res. 2019:47(D1) | 15 Citations (from Europe PMC, 2024-04-20)

Ranking

All databases:
2604/6000 (56.617%)
Gene genome and annotation:
785/1675 (53.194%)
Genotype phenotype and variation:
377/852 (55.869%)
2604
Total Rank
14
Citations
2.8
z-index

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Record metadata

Created on: 2019-01-04
Curated by:
Lina Ma [2019-01-23]
Dong Zou [2019-01-12]
Dong Zou [2019-01-04]