Vesiclepedia


37953359	Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository. [PMID: 37953359] Sai V Chitti, Sriram Gummadi, Taeyoung Kang, Sanjay Shahi, Akbar L Marzan, Christina Nedeva, Rahul Sanwlani, Kyle Bramich, Sarah Stewart, Monika Petrovska, Biswadeep Sen, Alper Ozkan, Maria Akinfenwa, Pamali Fonseka, Suresh Mathivanan Abstract Vesiclepedia (http://www.microvesicles.org) is a free web-based compendium of DNA, RNA, proteins, lipids and metabolites that are detected or associated with extracellular vesicles (EVs) and extracellular particles (EPs). EVs are membranous vesicles that are secreted ubiquitously by cells from all domains of life from archaea to eukaryotes. In addition to EVs, it was reported recently that EPs like exomeres and supermeres are secreted by some mammalian cells. Both EVs and EPs contain proteins, nucleic acids, lipids and metabolites and has been proposed to be implicated in several key biological functions. Vesiclepedia catalogues proteins, DNA, RNA, lipids and metabolites from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 3533 EV studies, 50 550 RNA entries, 566 911 protein entries, 3839 lipid entries, 192 metabolite and 167 DNA entries. Quantitative data for 62 822 entries from 47 EV studies is available in Vesiclepedia. The datasets available in Vesiclepedia can be downloaded as tab-delimited files or accessible through the FunRich-based Vesiclepedia plugin. Nucleic Acids Res. 2024:52(D1) \| 49 Citations (from Europe PMC, 2025-03-22)
30395310	Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles. [PMID: 30395310] Pathan M, Fonseka P, Chitti SV, Kang T, Sanwlani R, Van Deun J, Hendrix A, Mathivanan S. Abstract Extracellular vesicles (EVs) are membranous vesicles that are released by both prokaryotic and eukaryotic cells into the extracellular microenvironment. EVs can be categorised as exosomes, ectosomes or shedding microvesicles and apoptotic bodies based on the mode of biogenesis. EVs contain biologically active cargo of nucleic acids, proteins, lipids and metabolites that can be altered based on the precise state of the cell. Vesiclepedia (http://www.microvesicles.org) is a web-based compendium of RNA, proteins, lipids and metabolites that are identified in EVs from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 1254 EV studies, 38 146 RNA entries, 349 988 protein entries and 639 lipid/metabolite entries. Vesiclepedia is publicly available and allows users to query and download EV cargo based on different search criteria. The mode of EV isolation and characterization, the biophysical and molecular properties and EV-METRIC are listed in the database aiding biomedical scientists in assessing the quality of the EV preparation and the corresponding data obtained. In addition, FunRich-based Vesiclepedia plugin is incorporated aiding users in data analysis. Nucleic Acids Res. 2019:47(D1) \| 404 Citations (from Europe PMC, 2025-03-22)

Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository. [PMID: 37953359]

Sai V Chitti, Sriram Gummadi, Taeyoung Kang, Sanjay Shahi, Akbar L Marzan, Christina Nedeva, Rahul Sanwlani, Kyle Bramich, Sarah Stewart, Monika Petrovska, Biswadeep Sen, Alper Ozkan, Maria Akinfenwa, Pamali Fonseka, Suresh Mathivanan

Abstract

Vesiclepedia (http://www.microvesicles.org) is a free web-based compendium of DNA, RNA, proteins, lipids and metabolites that are detected or associated with extracellular vesicles (EVs) and extracellular particles (EPs). EVs are membranous vesicles that are secreted ubiquitously by cells from all domains of life from archaea to eukaryotes. In addition to EVs, it was reported recently that EPs like exomeres and supermeres are secreted by some mammalian cells. Both EVs and EPs contain proteins, nucleic acids, lipids and metabolites and has been proposed to be implicated in several key biological functions. Vesiclepedia catalogues proteins, DNA, RNA, lipids and metabolites from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 3533 EV studies, 50 550 RNA entries, 566 911 protein entries, 3839 lipid entries, 192 metabolite and 167 DNA entries. Quantitative data for 62 822 entries from 47 EV studies is available in Vesiclepedia. The datasets available in Vesiclepedia can be downloaded as tab-delimited files or accessible through the FunRich-based Vesiclepedia plugin.

Nucleic Acids Res. 2024:52(D1) | 49 Citations (from Europe PMC, 2025-03-22)

Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles. [PMID: 30395310]

Pathan M, Fonseka P, Chitti SV, Kang T, Sanwlani R, Van Deun J, Hendrix A, Mathivanan S.

Abstract

Extracellular vesicles (EVs) are membranous vesicles that are released by both prokaryotic and eukaryotic cells into the extracellular microenvironment. EVs can be categorised as exosomes, ectosomes or shedding microvesicles and apoptotic bodies based on the mode of biogenesis. EVs contain biologically active cargo of nucleic acids, proteins, lipids and metabolites that can be altered based on the precise state of the cell. Vesiclepedia (http://www.microvesicles.org) is a web-based compendium of RNA, proteins, lipids and metabolites that are identified in EVs from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 1254 EV studies, 38 146 RNA entries, 349 988 protein entries and 639 lipid/metabolite entries. Vesiclepedia is publicly available and allows users to query and download EV cargo based on different search criteria. The mode of EV isolation and characterization, the biophysical and molecular properties and EV-METRIC are listed in the database aiding biomedical scientists in assessing the quality of the EV preparation and the corresponding data obtained. In addition, FunRich-based Vesiclepedia plugin is incorporated aiding users in data analysis.

Nucleic Acids Res. 2019:47(D1) | 404 Citations (from Europe PMC, 2025-03-22)

URL:	http://www.microvesicles.org
Full name:
Description:	a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles.
Year founded:	2019
Last update:
Version:
Accessibility:	Accessible
Country/Region:	Australia

Data type:	DNA Protein RNA
Data object:	Animal
Database category:	Gene genome and annotation Literature Metadata
Major species:	Homo sapiens Acinetobacter baumannii Bacillus anthracis Burkholderia pseudomallei Candida albicans Canis lupus Cryptococcus neoformans Drosophila melanogaster Mus musculus Sus scrofa
Keywords:	extracellular vesicles lipid

University/Institution:	La Trobe Institute
Address:	La Trobe Institute for Molecular Sciences, Melbourne, Australia
City:
Province/State:
Country/Region:	Australia
Contact name (PI/Team):	Suresh Mathivanan
Contact email (PI/Helpdesk):	S.Mathivanan@latrobe.edu.au

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Database Commons a catalog of worldwide biological databases