| URL: | https://repicmod.uchicago.edu/repic |
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| Description: | The REPIC (RNA EPItranscriptome Collection) database records about 10 million peaks called from publicly available m6A-seq and MeRIP-seq data . These data were collected from 672 samples of 49 studies, covering 61 cell lines or tissues in 11 organisms. REPIC allows users to query N6-methyladenosine (m6A) modification sites by specific cell lines or tissue types. In addition, it integrates m6A/MeRIP-seq data with 1418 histone ChIP-seq and 118 DNase-seq data tracks from the ENCODE project in a modern genome browser to present a comprehensive atlas of m6A methylation sites, histone modification sites, and chromatin accessibility regions. |
| Year founded: | 2020 |
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| Accessibility: |
Accessible
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| Country/Region: | United States |
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| University/Institution: | University of Chicago |
| Address: | Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA. mengjiechen@uchicago.edu. |
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| Country/Region: | United States |
| Contact name (PI/Team): | Mengjie Chen |
| Contact email (PI/Helpdesk): | mengjiechen@uchicago.edu |
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REPIC: a database for exploring the N-methyladenosine methylome. [PMID: 32345346]
The REPIC (RNA EPItranscriptome Collection) database records about 10 million peaks called from publicly available mA-seq and MeRIP-seq data using our unified pipeline. These data were collected from 672 samples of 49 studies, covering 61 cell lines or tissues in 11 organisms. REPIC allows users to query N-methyladenosine (mA) modification sites by specific cell lines or tissue types. In addition, it integrates mA/MeRIP-seq data with 1418 histone ChIP-seq and 118 DNase-seq data tracks from the ENCODE project in a modern genome browser to present a comprehensive atlas of mA methylation sites, histone modification sites, and chromatin accessibility regions. REPIC is accessible at https://repicmod.uchicago.edu/repic. |