IAnimal


36300629	IAnimal: a cross-species omics knowledgebase for animals. [PMID: 36300629] Fu Y, Liu H, Dou J, Wang Y, Liao Y, Huang X, Tang Z, Xu J, Yin D, Zhu S, Liu Y, Shen X, Liu H, Liu J, Yang X, Zhang Y, Xiang Y, Li J, Zheng Z, Zhao Y, Ma Y, Wang H, Du X, Xie S, Xu X, Zhang H, Yin L, Zhu M, Yu M, Li X, Liu X, Zhao S. Abstract With the exponential growth of multi-omics data, its integration and utilization have brought unprecedented opportunities for the interpretation of gene regulation mechanisms and the comprehensive analyses of biological systems. IAnimal (https://ianimal.pro/), a cross-species, multi-omics knowledgebase, was developed to improve the utilization of massive public data and simplify the integration of multi-omics information to mine the genetic mechanisms of objective traits. Currently, IAnimal provides 61 191 individual omics data of genome (WGS), transcriptome (RNA-Seq), epigenome (ChIP-Seq, ATAC-Seq) and genome annotation information for 21 species, such as mice, pigs, cattle, chickens, and macaques. The scale of its total clean data has reached 846.46 TB. To better understand the biological significance of omics information, a deep learning model for IAnimal was built based on BioBERT and AutoNER to mine 'gene' and 'trait' entities from 2 794 237 abstracts, which has practical significance for comprehending how each omics layer regulates genes to affect traits. By means of user-friendly web interfaces, flexible data application programming interfaces, and abundant functional modules, IAnimal enables users to easily query, mine, and visualize characteristics in various omics, and to infer how genes play biological roles under the influence of various omics layers. Nucleic Acids Res. 2022:() \| 9 Citations (from Europe PMC, 2025-03-22)

IAnimal: a cross-species omics knowledgebase for animals. [PMID: 36300629]

Fu Y, Liu H, Dou J, Wang Y, Liao Y, Huang X, Tang Z, Xu J, Yin D, Zhu S, Liu Y, Shen X, Liu H, Liu J, Yang X, Zhang Y, Xiang Y, Li J, Zheng Z, Zhao Y, Ma Y, Wang H, Du X, Xie S, Xu X, Zhang H, Yin L, Zhu M, Yu M, Li X, Liu X, Zhao S.

Abstract

With the exponential growth of multi-omics data, its integration and utilization have brought unprecedented opportunities for the interpretation of gene regulation mechanisms and the comprehensive analyses of biological systems. IAnimal (https://ianimal.pro/), a cross-species, multi-omics knowledgebase, was developed to improve the utilization of massive public data and simplify the integration of multi-omics information to mine the genetic mechanisms of objective traits. Currently, IAnimal provides 61 191 individual omics data of genome (WGS), transcriptome (RNA-Seq), epigenome (ChIP-Seq, ATAC-Seq) and genome annotation information for 21 species, such as mice, pigs, cattle, chickens, and macaques. The scale of its total clean data has reached 846.46 TB. To better understand the biological significance of omics information, a deep learning model for IAnimal was built based on BioBERT and AutoNER to mine 'gene' and 'trait' entities from 2 794 237 abstracts, which has practical significance for comprehending how each omics layer regulates genes to affect traits. By means of user-friendly web interfaces, flexible data application programming interfaces, and abundant functional modules, IAnimal enables users to easily query, mine, and visualize characteristics in various omics, and to infer how genes play biological roles under the influence of various omics layers.

Nucleic Acids Res. 2022:() | 9 Citations (from Europe PMC, 2025-03-22)

URL:	http://ianimal.pro/
Full name:	A cross-species omics knowledgebase for animals
Description:	IAnimal is a cross-species, multi-omics knowledgebase. It provides comprehensive structured multi-omics data for a wide range of animal species, abundant omics data mining and visualization tools, and intelligent integration analysis algorithms for multi-omics data. In the present version, IAnimal provides 61,191 WGS, RNA-Seq, ChIP-Seq, and ATAC-Seq individual information and genome annotation information for 21 species.
Year founded:	2022
Last update:	20220915
Version:	v1.0
Accessibility:	Accessible
Country/Region:	China

Data type:	DNA Other RNA
Data object:	Animal
Database category:	Expression Gene genome and annotation Literature Modification Phylogeny and homology
Major species:	Sus scrofa Bos taurus Ovis aries Equus caballus Capra hircus Equus asinus Balaenoptera musculus Mus musculus Macaca mulatta Canis familiaris Felis catus Camelus dromedarius Loxodonta africana Ursus thibetanus Gallus gallus Anas platyrhynchos Anser cygnoides Oryctolagus cuniculus Ailuropoda melanoleuca Panthera leo Panthera tigris
Keywords:	multi-omics data Cross Species Comparison literature mining application programming interface

University/Institution:	Huazhong Agricultural University
Address:	No.1,Shizishan Street · Hongshan District · Wuhan · Hubei Province · 430070 · P.R.China
City:	Wuhan
Province/State:	Hubei
Country/Region:	China
Contact name (PI/Team):	Yuhua Fu
Contact email (PI/Helpdesk):	yhfu@mail.hzau.edu.cn

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Database Commons a catalog of worldwide biological databases