gutMDisorder


36215029	gutMDisorder v2.0: a comprehensive database for dysbiosis of gut microbiota in phenotypes and interventions. [PMID: 36215029] Qi C, Cai Y, Qian K, Li X, Ren J, Wang P, Fu T, Zhao T, Cheng L, Shi L, Zhang X. Abstract Gut microbiota plays a significant role in maintaining host health, and conversely, disorders potentially lead to dysbiosis, an imbalance in the composition of the gut microbial community. Intervention approaches, such as medications, diets, and several others, also alter the gut microbiota in either a beneficial or harmful direction. In 2020, the gutMDisorder was developed to facilitate researchers in the investigation of dysbiosis of gut microbes as occurs in various disorders as well as with therapeutic interventions. The database has been updated this year, following revision of previous publications and newly published reports to manually integrate confirmed associations under multitudinous conditions. Additionally, the microbial contents of downloaded gut microbial raw sequencing data were annotated, the metadata of the corresponding hosts were manually curated, and the interactive charts were developed to enhance visualization. The improvements have assembled into gutMDisorder v2.0, a more advanced search engine and an upgraded web interface, which can be freely accessed via http://bio-annotation.cn/gutMDisorder/. Nucleic Acids Res. 2022:() \| 18 Citations (from Europe PMC, 2025-04-12)
31584099	gutMDisorder: a comprehensive database for dysbiosis of the gut microbiota in disorders and interventions. [PMID: 31584099] Cheng L, Qi C, Zhuang H, Fu T, Zhang X. Abstract gutMDisorder (http://bio-annotation.cn/gutMDisorder), a manually curated database, aims at providing a comprehensive resource of dysbiosis of the gut microbiota in disorders and interventions. Alterations in the composition of the gut microbial community play crucial roles in the development of chronic disorders. And the beneficial effects of drugs, foods and other intervention measures on disorders could be microbially mediated. The current version of gutMDisorder documents 2263 curated associations between 579 gut microbes and 123 disorders or 77 intervention measures in Human, and 930 curated associations between 273 gut microbes and 33 disorders or 151 intervention measures in Mouse. Each entry in the gutMDisorder contains detailed information on an association, including an intestinal microbe, a disorder name, intervention measures, experimental technology and platform, characteristic of samples, web sites for downloading the sequencing data, a brief description of the association, a literature reference, and so on. gutMDisorder provides a user-friendly interface to browse, retrieve each entry using gut microbes, disorders, and intervention measures. It also offers pages for downloading all the entries and submitting new experimentally validated associations. Nucleic Acids Res. 2020:48(D1) \| 101 Citations (from Europe PMC, 2025-04-12)

gutMDisorder v2.0: a comprehensive database for dysbiosis of gut microbiota in phenotypes and interventions. [PMID: 36215029]

Qi C, Cai Y, Qian K, Li X, Ren J, Wang P, Fu T, Zhao T, Cheng L, Shi L, Zhang X.

Abstract

Gut microbiota plays a significant role in maintaining host health, and conversely, disorders potentially lead to dysbiosis, an imbalance in the composition of the gut microbial community. Intervention approaches, such as medications, diets, and several others, also alter the gut microbiota in either a beneficial or harmful direction. In 2020, the gutMDisorder was developed to facilitate researchers in the investigation of dysbiosis of gut microbes as occurs in various disorders as well as with therapeutic interventions. The database has been updated this year, following revision of previous publications and newly published reports to manually integrate confirmed associations under multitudinous conditions. Additionally, the microbial contents of downloaded gut microbial raw sequencing data were annotated, the metadata of the corresponding hosts were manually curated, and the interactive charts were developed to enhance visualization. The improvements have assembled into gutMDisorder v2.0, a more advanced search engine and an upgraded web interface, which can be freely accessed via http://bio-annotation.cn/gutMDisorder/.

Nucleic Acids Res. 2022:() | 18 Citations (from Europe PMC, 2025-04-12)

gutMDisorder: a comprehensive database for dysbiosis of the gut microbiota in disorders and interventions. [PMID: 31584099]

Cheng L, Qi C, Zhuang H, Fu T, Zhang X.

Abstract

gutMDisorder (http://bio-annotation.cn/gutMDisorder), a manually curated database, aims at providing a comprehensive resource of dysbiosis of the gut microbiota in disorders and interventions. Alterations in the composition of the gut microbial community play crucial roles in the development of chronic disorders. And the beneficial effects of drugs, foods and other intervention measures on disorders could be microbially mediated. The current version of gutMDisorder documents 2263 curated associations between 579 gut microbes and 123 disorders or 77 intervention measures in Human, and 930 curated associations between 273 gut microbes and 33 disorders or 151 intervention measures in Mouse. Each entry in the gutMDisorder contains detailed information on an association, including an intestinal microbe, a disorder name, intervention measures, experimental technology and platform, characteristic of samples, web sites for downloading the sequencing data, a brief description of the association, a literature reference, and so on. gutMDisorder provides a user-friendly interface to browse, retrieve each entry using gut microbes, disorders, and intervention measures. It also offers pages for downloading all the entries and submitting new experimentally validated associations.

Nucleic Acids Res. 2020:48(D1) | 101 Citations (from Europe PMC, 2025-04-12)

URL:	http://bio-annotation.cn/gutMDisorder/
Full name:
Description:	gutMDisoeder is a comprehensive and user-friendly database for gut microbial dysbiosis under various phenotypes and therapeutic interventions from literature and raw data in human and mouse.
Year founded:	2020
Last update:	2022-6-1
Version:	2.0
Accessibility:	Accessible
Country/Region:	China

Data type:	Other
Data object:	Bacteria
Database category:	Interaction Literature Raw bio-data
Major species:	Homo sapiens Mus musculus
Keywords:	Gut Microbiota Intervention Phenotype

University/Institution:	Harbin Medical University
Address:
City:	Harbin
Province/State:	Heilongjiang
Country/Region:	China
Contact name (PI/Team):	Liang Cheng
Contact email (PI/Helpdesk):	liangcheng@hrbmu.edu.cn

Database Commons
a catalog of worldwide biological databases

a catalog of worldwide biological databases

Database Profile

General information

Funding support

Classification & Tag

Contact information

Publications

Ranking

Community reviews

Word cloud

Tags

Related Databases

Record metadata

Research & Resources

Featured

Alliance & Collaboration

Conference & Outreach

About

Database Commons a catalog of worldwide biological databases