HGD


36318261	HGD: an integrated homologous gene database across multiple species. [PMID: 36318261] Duan G, Wu G, Chen X, Tian D, Li Z, Sun Y, Du Z, Hao L, Song S, Gao Y, Xiao J, Zhang Z, Bao Y, Tang B, Zhao W. Abstract Homology is fundamental to infer genes' evolutionary processes and relationships with shared ancestry. Existing homolog gene resources vary in terms of inferring methods, homologous relationship and identifiers, posing inevitable difficulties for choosing and mapping homology results from one to another. Here, we present HGD (Homologous Gene Database, https://ngdc.cncb.ac.cn/hgd), a comprehensive homologs resource integrating multi-species, multi-resources and multi-omics, as a complement to existing resources providing public and one-stop data service. Currently, HGD houses a total of 112 383 644 homologous pairs for 37 species, including 19 animals, 16 plants and 2 microorganisms. Meanwhile, HGD integrates various annotations from public resources, including 16 909 homologs with traits, 276 670 homologs with variants, 398 573 homologs with expression and 536 852 homologs with gene ontology (GO) annotations. HGD provides a wide range of omics gene function annotations to help users gain a deeper understanding of gene function. Nucleic Acids Res. 2022:() \| 5 Citations (from Europe PMC, 2025-03-15)

HGD: an integrated homologous gene database across multiple species. [PMID: 36318261]

Duan G, Wu G, Chen X, Tian D, Li Z, Sun Y, Du Z, Hao L, Song S, Gao Y, Xiao J, Zhang Z, Bao Y, Tang B, Zhao W.

Homology is fundamental to infer genes' evolutionary processes and relationships with shared ancestry. Existing homolog gene resources vary in terms of inferring methods, homologous relationship and identifiers, posing inevitable difficulties for choosing and mapping homology results from one to another. Here, we present HGD (Homologous Gene Database, https://ngdc.cncb.ac.cn/hgd), a comprehensive homologs resource integrating multi-species, multi-resources and multi-omics, as a complement to existing resources providing public and one-stop data service. Currently, HGD houses a total of 112 383 644 homologous pairs for 37 species, including 19 animals, 16 plants and 2 microorganisms. Meanwhile, HGD integrates various annotations from public resources, including 16 909 homologs with traits, 276 670 homologs with variants, 398 573 homologs with expression and 536 852 homologs with gene ontology (GO) annotations. HGD provides a wide range of omics gene function annotations to help users gain a deeper understanding of gene function.

Nucleic Acids Res. 2022:() | 5 Citations (from Europe PMC, 2025-03-15)

URL:	https://ngdc.cncb.ac.cn/hgd
Full name:	Homologous gene database
Description:	A data portal of homologous genes across multiple species
Year founded:	2022
Last update:	2022
Version:	1.0
Accessibility:	Accessible
Country/Region:	China

Data type:	DNA Other Protein
Data object:	Animal Fungi Plant
Database category:	Phylogeny and homology
Major species:	Ailuropoda melanoleuca Apis mellifera Arabidopsis thaliana Gallus gallus Bombyx mori Bos taurus Brassica napus Caenorhabditis elegans Canis familiaris Capsicum annuum Cucumis sativus Danio rerio Drosophila melanogaster Equus caballus Escherichia coli Felis catus Glycine max Gossypium hirsutum Homo sapiens Macaca mulatta Manihot esculenta Meleagris gallopavo Mus musculus Oryza sativa Pan troglodytes Phoenix dactylifera Populus trichocarpa Rattus norvegicus Saccharomyces cerevisiae Solanum lycopersicum Solanum tuberosum Sorghum bicolor Sus scrofa Triticum aestivum Vitis vinifera Xenopus tropicalis Zea mays
Keywords:	homologous gene multi-omics data

University/Institution:	Beijing Institute of Genomics, Chinese Academy of Sciences
Address:
City:
Province/State:
Country/Region:	China
Contact name (PI/Team):	HGD group
Contact email (PI/Helpdesk):	hgd@big.ac.cn

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Database Commons a catalog of worldwide biological databases