Editome Disease Knowledgebase
Editome-disease associations based on
literature curation and integrative analysis
RNA binding proteins (RBPs) play a crucial role in modulating transcription and translation, often exhibiting dysregulation in human cancers and diseases. RNA editing sites that are located within the RNA binding target sequences of RBPs potentially impact the interaction dynamics between the RBPs and their target genes. Here we collect 71,284 differential RNA editing sites associated with 75 RBPs based on the ENCORI/starBase database (Li JH. et al, Nucleic Acids Research, 2014) and integrate 458,187 associations between differential RNA editing sites and RBPs in EDK. Meanwhile, the disease information of differential editing sites could be also found in the "View Detail" column.
| View Detail | Editing Site | Edited Gene ID | Gene Symbol | RNA Binding Protein | Binding Start Position | Binding End Position | Motif Length | ENCORI Interaction ID |
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