EDK Editome Disease Knowledgebase

  1. Home
  2. miRNA
  3. hsa-miR-200b

hsa-miR-200b

miRNA ID hsa-miR-200b
Editing sites 1
Species Human
miRBase MI0000342
PMID 28411194
Description miR-200b editing shows correlations with TP53 in breast cancers. High editing level in miR-200b is associated with worse patient survival.
Disease Breast Cancer; Gastric Cancer; Head and Neck Cancer; Endometrial Cancer; Thyroid Cancer;
Sequence

Editing sites

Enzyme Editing Type Editing-Level Target Change Regulation Target Relationship Correlation Editing Effect Phenotype Disease PMID
ADAR1;ADAR2 A-to-G Increase TP53->TP53 Associated with TP53 Correlated Positive miR-200b editing shows correlations with TP53 in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase TP53->TP53 Associated with TP53 Correlated Positive miR-200b editing shows correlations with TP53 in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase TP53->TP53 Associated with TP53 Correlated Positive miR-200b editing shows correlations with TP53 in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase BRAF->BRAF Associated with BRAF Correlated Positive miR-200b editing shows correlations with BRAF in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase NRAS->NRAS Associated with NRAS Correlated Positive miR-200b editing shows correlations with NRAS in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase CDH1->CDH1 Associated with CDH1 Correlated Positive miR-200b editing shows correlations with CDH1 in several cancer. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase ZEB1->ZEB1 Inhibit ZEB1 expression Correlated Positive miR-200b can promote cell invasion and migration through its impaired ability to inhibit ZEB1/ZEB2. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase ZEB2->ZEB2 Inhibit ZEB2 expression Correlated Positive miR-200b can promote cell invasion and migration through its impaired ability to inhibit ZEB1/ZEB2. Inhibit survival 28411194
ADAR1;ADAR2 A-to-G Increase LIFR->LIFR Inhibit LIFR expression Correlated Positive RNA editing promotes the ability to repress metastasis suppressor LIFR. Inhibit survival 28411194