Are you curious about what diseases might be affected by a cluster of interested editing sites? To achieve this goal, we developed "Disease Prediction", an algorithm tool based on hypergeometric test method. "Disease Prediction" provides a list of predictive associations according to the differential RNA editing sites (including hit ratio, average risk score, and max risk score), which helps users to assess the strength of the relationship between a cluster of interested editing sites and specific diseases. Additionally, it also provides associations between these sites and diseases based on literature curation.