EDK Editome Disease Knowledgebase

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Editing Type:
Enzyme:
Editing Level:
Correlation:
Gene Symbol Aliases Editing Sites Enzyme Editing Type Molecular Consequence Editing Level Correlation Phenotype Disease
CTSS - 41 ADAR1 A-to-I mRNA stability change Present Negative Reduce atherosclerosis and angiogenesis
AZIN1 - 2 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Present Positive Promote tumor cellular proliferation;Promote aggressive behaviors in tumor progression
FLNB - 1 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Increased Positive Increase RNA editing level in disease; Induce malignant phenotypes during tumor progression
COPA - 1 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Increased Positive Affect tumor pathogenesis
IGFBP7 - 3 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Decreased Positive Inhibit tumor cell apoptosis; Reduce RNA editing event promote tumor cell proliferation
GRIA2 GLUR2 1 ADAR2 A-to-I Nonsynonymous substitution Decreased Negative Reduce RNA editing in disease
GRIA3 GLUR3 1 ADAR2 A-to-I Nonsynonymous substitution Decreased Negative Promote recovery of spinal core injury
GRIA4 GLUR4 1 ADAR2 A-to-I Nonsynonymous substitution Decreased Negative Promote recovery of spinal core injury
GRIK1 GLUR5 1 ADAR2 A-to-I Nonsynonymous substitution Decreased Negative Reduce RNA editing in disease
GRIK2 GLUR6 1 ADAR2 A-to-I Nonsynonymous substitution Decreased Negative Reduce RNA editing in disease
HTR2C - 6 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Present Positive Induce disease
RHOQ - 1 NA A-to-I Nonsynonymous substitution Increased Positive Promote recurrence
PINK1 - 1 ADAR2 A-to-I Nonsynonymous substitution Present Negative Repair mitophagy
EDNRB ETB 1 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Present Positive Induce disease
BLCAP - 12 ADAR1;ADAR2 A-to-I Nonsynonymous substitution; mRNA expression change Decreased Negative Reduce RNA editing in disease
SLC1A2 EAAT2 1 ADAR1;ADAR2 A-to-I Alternative splicing Present Positive Affect disease processing
PTPN6 - 1 NA A-to-I Alternative splicing Present Positive Affect disease processing
LDLR - 1 NA G-to-C Alternative splicing Present Positive Reduce hypercholesterolemia
CDC14B - 13 ADAR2 A-to-I - Decreased Negative Reduce RNA editing in disease
TPH2 - 5 APOBEC A-to-I; G-to-A; C-to-U Alternative splicing Present Positive Affect disease processing
HNRNPK - 1 APOBEC3B G-to-A Nonsynonymous substitution Present Positive Affect disease processing
PODXL - 1 ADAR1;ADAR2 A-to-I Nonsynonymous substitution Absent Positive Reduce tumorigenic ability
GLI1 - 1 ADAR1 A-to-I Nonsynonymous substitution Present Positive Increase RNA editing level in disease
NF1 - 1 NA C-to-U Nonsynonymous substitution Increased Positive Increase RNA editing level in disease
ARPIN - 2 ADAR1;ADAR2;ADAR3 A-to-I - Present Positive Promote the disease risk
DHFR - 25 ADAR1 G-to-A mRNA expression change Increased Positive Promote tumor cell proliferation
NEIL1 - 1 ADAR1 A-to-I Nonsynonymous substitution Increased Positive Increase RNA editing level in disease
WT1 - 1 APOBEC3A G-to-A Nonsynonymous substitution Present Positive Induce mutation of wilms tumor and acute myeloid leukemia
GABRA-3 - 1 ADAR1;ADAR2 G-to-A Nonsynonymous substitution Present Positive Affect the variability GABAA receptors in sensitivity to drugs
SLC22A3 - 1 ADAR2 A-to-I Nonsynonymous substitution Present Positive Promote the tumor progression and malignant development
FLNA - 1 ADAR1;ADAR2 NA Nonsynonymous substitution Decreased Negative Exacerbation the psoriasis
CDK13 - 2 ADAR1 A-to-I Nonsynonymous substitution Increased Positive Affect HCC tumor tissues and associated with poor prognosis
HNRPLL SRRF; HNRPLL 3 ADAR1;ADAR2 NA Alternative splicing Present Positive RNA editing of HNRPLL generates a novel splicing variant linked to cell proliferation
COG3 SEC34 1 ADAR2 NA Recoding Present Negative Over-editing (>40%) at the COG3 I/V site with a worse prognosis in GBM patients
PDE8A HsT19550 5 ADAR1 NA mRNA expression change Increased Positive RNA editing play an important role in the initiation and propagation of SLE pathogenesis;RNA-editing providing a marker for discriminating between suicides and control groups
XIAP API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3 31 ADAR1 NA protein products expression change Present Positive Edited XIAP suppressed the XIAP-dependent apoptotic response
MDM2 HDMX; hdm2; ACTFS 5 ADAR1 NA protein products expression change Present Positive Edited MDM2 suppressed the MDM2-dependent apoptotic response
DFFA DFF1; ICAD; DFF-45 1 ADAR1 A-to-I miRNA binding sites gain Present NA Dfferential RNA editing of DFFA in two cell lines(MCF-7
ABCA5 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ADAM22 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ADGRB3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ANAPC5 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ANK3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ARHGEF11 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ARNT2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ASIC2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ATM 21 ADAR1 A-to-I mRNA expression change Increased Positive Increasing the editing in the 3′UTRs of ATM transcripts in tumors
ATP2B2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ATRNL1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
C10orf113 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
C11orf58 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
C1orf95 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CABP1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CACNB2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CADM2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CADPS 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CCDC15 4 ADAR1 A-to-I Alternative splicing change Presence Positive Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppressive
CCDC84 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CDS2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CERS4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CLASP1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CLASP2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CNTNAP2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CNTNAP4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
COA4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CSMD1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
CTNNA2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DANT2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DGCR5 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DGKZ 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DLG2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DLGAP1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DNAJC6 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
DPP10 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
EPS15 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FAK 1 ADAR1 A-to-I mRNA stability change Presence Negative FAK blocked ADAR-induced invasiveness of LUAD cells
FAM155A 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FGF12 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FGF14 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FMNL2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FRMD4A 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FTX 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
FUT9 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GFOD2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GINS4 44 ADAR1 A-to-I mRNA expression change Increased Positive Increasing the editing in the 3′UTRs of GINS4 transcripts in tumors
GNL3L 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GOLGA3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GPCPD1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GPM6A 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
GRM7 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
HLTF 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
HP1BP3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
IBA57 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
IFNGR1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ILDR2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
JMJD1C 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KATNBL1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KCNIP4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KCNQ3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KCTD16 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KHDRBS3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KIAA1211L 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
KLHL11 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LAMTOR3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LIMCH1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LINC-PINT 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LOC101928961 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LOC171391 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
LRRC4C 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MAGI2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MAP4K3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MAPK10 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MATR3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MED13 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
METTL6 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MIAT 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MIR22HG 1 NA NA NA NA Negative It is a potential as a biomarker for several cancers
MKLN1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MON2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MSRA 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MTPAP 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MTR 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
MTUS1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NCKAP1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NOVA1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NRXN1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NRXN3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NSMAF 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NUP43 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
NXPE3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
OXR1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PAPD4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PCDH9 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PGK1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PLCB1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
POLH 156 ADAR1 A-to-I mRNA expression change Increased Positive Increasing the editing in the 3′UTRs of POLH transcripts in tumors
POLR2F 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PPP2R2B 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PREPL 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
PTPRD 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
R3HDM1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RALYL 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RBM5 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RELL2 1 ADAR2 A-to-I Alternative splicing change Presence Positive Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppressive
RGS7 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RIMS2 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RTN3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
RTN4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SERPINI1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SFXN5 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SHC3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SHISA9 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SHTN1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SLC25A27 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
SRSF5 1 NA NA NA NA Negative RNA editing could contribute towards aberrant synaptic formation in ASD
STRBP 1 ADAR1 A-to-I mRNA expression change Presence Positive SRSF5 is involved in cancer development
SYT1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
TMEM161B-AS1 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
TRIM65 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
TTLL7 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
UBE2D3 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
VEZT 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
VPS13C 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
WDR33 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
XKR4 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
XKR6 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZNF264 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZNF37BP 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZNF529 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZNF680 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZNF708 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
ZYG11B 1 ADAR1 A-to-I mRNA expression change Presence Positive RNA editing could contribute towards aberrant synaptic formation in ASD
Editing Type:
Enzyme:
Editing Level:
Correlation:
miRNA ID Editing Sites Enzyme Editing Type Molecular Consequence Editing-Level Target Change Correlation Phenotype Disease
hsa-mir-214 2 ADAR2 U-to-C miRNA and its target gene expression change Increased
  • Rab15->Rab15
 - Occur in tumor
hsa-mir-122 1 ADAR2 A-to-I miRNA and its target gene expression change Increased - - Occur in tumor
hsa-miR-200b 1 ADAR1;ADAR2 A-to-I - Increased
  • TP53->TP53
  • BRAF->BRAF
  • NRAS->NRAS
  • CDH1->CDH1
  • ZEB1->ZEB1
  • ZEB2->ZEB2
  • LIFR->LIFR
 - Inhibit survival capability
hsa-miR-99a 1 ADAR1;ADAR3 A-to-I - Increased
  • TP53->TP53
  • PIK3CA->PIK3CA
  • MAP3K1->MAP3K1
  • HRAS->HRAS
  • NRAS->NRAS
 Positive Affect disease
hsa-miR-376a 1 ADAR1 A-to-I Retargeting of miRNA Increased
  • RAP2A->AMFR
 Positive Promote tumor migration and invasion
hsa-miR-455-5p 2 ADAR1 A-to-I Target gene expression change Absent
  • CPEB1->CPEB1
 Negative Inhibit tumor growth and metastasis
hsa-let-7a-1 2 ADAR1 A-to-I Regulate miRNA biogenesis Increased - Negative Promote survival capability
hsa-miR-132-3p 2 - A-to-I miRNA expression change Increased - Positive Affect disease
hsa-mir-27b 1 - A-to-I - Increased - Positive Promote plasma levels of high-density lipoprotein
hsa-miR-605 1 - A-to-I - Increased - Positive Promote plasma levels of high-density lipoprotein
hsa-miR-378a-3p 1 ADAR1 A-to-I Target gene expression change Increased
  • PARVA->PARVA
 Positive Inhibit tumor progression
hsa-miR-589-3p 3 ADAR2 A-to-I Retargeting of miRNA Increased
  • PCDH9->ADAM12
 Negative Inhibit tumor proliferation, migration and invasion
hsa-miR-221 2 ADAR2 A-to-I miRNA expression change Increased - Positive Affect tumor migration and invasion
hsa-miR-222 2 ADAR2 A-to-I miRNA expression change Increased - Positive Affect tumor migration and invasion
hsa-miR-381 2 ADAR2 A-to-I miRNA expression change Increased - Positive Affect tumor migration and invasion
hsa-miR-142-3p 1 ADAR2 U-to-C miRNA expression change Increased - Positive Affect cell migration and proliferation
has-mir-3157 1 ADAR1 A-to-G miRNA and its target gene expression change Increase
  • NA
Positive Affect the pathogenesis of the disease
has-mir-6503 1 ADAR1 A-to-G miRNA and its target gene expression change Increase
  • NA
Positive Affect the pathogenesis of the disease
has-mir-200b 1 ADAR1 A-to-G miRNA and its target gene expression change Increase
  • NA->ZEB1
 Positive Its levels of editing correlate with a worse progression-free survival and disease stage
has-mir-149 1 ADAR1 A-to-G miRNA and its target gene expression change Increase
  • GSK3α
 Positive miRNA-149 is considered as both a bio-marker and a therapeutic target for treatment of mel
lncRNA name Editing site(s) Enzyme Editing Type Editing-Level Target Correlation Phenotype Disease
PCA3 1 ADAR1;ADAR2 A-to-I Present PRUNE2 Positive Promote prostate cancer malignant cell growth