Disease - EDK - BIG Data Center

Disease name	Glioma
Classfication	Cancer
Related Enzyme(s)
EFO	EFO:0005543
DOID	3070
OMIM	OMIM:137800 OMIM:607248 OMIM:613028 OMIM:613029 OMIM:613030 OMIM:613031 OMIM:613032 OMIM:613033
NCI	NCI:C3059
Definition	A glioma is a type of tumor that starts in the glial cells of the brain or the spine. Gliomas comprise about 30 per cent of all brain tumors and central nervous system tumors, and 80 per cent of all malignant brain tumors.

miRNA

Gene symbol	Disease	Enzyme	Editing Sites	Editing Type	miRBase	PMID	Description
hsa-miR-376a	Glioma	ADAR1	1	A-to-I	MI0000784	23093778	ADAR1 regulates let-7 miRNA biogenesis in an A-to-I editing dependent manner, it promotes the self-renewal and survival capability of chronic myeloid leukemia Leukemic stem cells.