EDK Editome Disease Knowledgebase

  1. Home
  2. RNA
  3. ATM

ATM

Gene symbol ATM
Aliases
Protein Name
Function
Species Human
Editing Sites 21
Disease Breast Cancer;
Description Editing was particularly increased in the 3′UTRs of ATM, GINS4 and POLH transcripts in tumors, which correlated with their mRNA expression.
RADR RADAR
REDIportal REDI portal
External links (Uniport); (NM id); (NCBI gene id); GeneCard; GTEx
Sequence

Editing sites

Enzyme Editing type Region NT Seq Position Molecular Consequence Editing Level Tissue Editing Effect Phenotype Disease name PMID
  • ADAR1
 A-to-I 3'UTR chr11:108155710 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108155718 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108173759 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236486 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236523 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236596 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236635 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236636 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236705 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108236707 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237738 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237815 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237818 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237832 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237880 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237890 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237953 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237957 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237975 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237976 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors
  • ADAR1
 A-to-I 3'UTR chr11:108237988 mRNA expression change Increased MCF10A, MCF12 and 184A1 mRNA expression change Increasing the editing in the 3′UTRs of ATM transcripts in tumors