EDK
Editome Disease Knowledgebase
BLCAP
| Gene symbol | BLCAP |
|---|---|
| Aliases | - |
| Protein Name | Notch homolog 2 N-terminal-like protein |
| Function | BLCAP is identified using a differential display procedure with tumor biopsies obtained from a noninvasive and an invasive bladder transitional cell carcinoma. |
| Species | Human |
| Editing Sites | 12 |
| Disease | Colorectal Cancer; Bladder Carcinoma; Lung Cancer; |
| Description | BLCAP-editing level is Decrease in bladder cancer, astrocytomas, colorectal cancer. |
| RADR | RADAR |
| REDIportal | REDI portal |
| External links | Q7Z3S9(Uniport); NM_006698 (NM id); 10904 (NCBI gene id); GeneCard; GTEx |
| Sequence |
Editing sites
| Enzyme | Editing type | Region | AA Seq Position | NT Seq Position | Codon Change | Amino Acid Change | Molecular Consequence | Editing Level | Tissue | Editing Effect | Phenotype | Disease name | PMID |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
A-to-I | CDS | 2 | 320 | UAU->UGU | Y->C | Nonsynonymous substitution | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 5 | 329 | CAG->CGG | Q->R | Nonsynonymous substitution | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 15 | 359 | AAG->AGG | K->R | Nonsynonymous substitution | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | 5'UTR | NA | 257 | NA | NA | mRNA expression change | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | 5'UTR | NA | 309 | NA | NA | mRNA expression change | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | 5'UTR | NA | 311 | NA | NA | mRNA expression change | Decreased | Bladder | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 2 | 320 | UAU->UGU | Y->C | Nonsynonymous substitution | Decreased | Brain | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 5 | 329 | CAG->CGG | Q->R | Nonsynonymous substitution | Decreased | Brain | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 15 | 359 | AAG->AGG | K->R | Nonsynonymous substitution | Decreased | Brain | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 2 | 320 | UAU->UGU | Y->C | Nonsynonymous substitution | Decreased | Mucosa | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 5 | 329 | CAG->CGG | E->R | Nonsynonymous substitution | Decreased | Mucosa | NA | Reduce RNA editing in disease | ||
|
A-to-I | CDS | 15 | 359 | AAG->AGG | K->R | Nonsynonymous substitution | Decreased | Mucosa | NA | Reduce RNA editing in disease |