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CCDC15

Gene symbol CCDC15
Aliases
Protein Name
Function
Species Human
Editing Sites 4
Disease Tumorigenesis;
Description Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppressive, respec- tively. More importantly, ADARs-mediated splicing changes indeed affect tumorigenesis, not merely byproducts of ADARs editing and binding.
RADR RADAR
REDIportal REDI portal
External links (Uniport); (NM id); (NCBI gene id); GeneCard; GTEx
Sequence

Editing sites

Enzyme Editing type Region NT Seq Position Molecular Consequence Editing Level Tissue Editing Effect Phenotype Disease name PMID
  • ADAR1
 A-to-I intronic chr11:124996215 Alternative splicing change Presence EC109 cells; HEK293T cells Alternative splicing change Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppress
  • ADAR1
 A-to-I intronic chr11:124996219 Alternative splicing change Presence EC109 cells; HEK293T cells Alternative splicing change Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppress
  • ADAR1
 A-to-I intronic chr11:124996223 Alternative splicing change Presence EC109 cells; HEK293T cells Alternative splicing change Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppress
  • ADAR1
 A-to-I intronic chr11:124996224 Alternative splicing change Presence EC109 cells; HEK293T cells Alternative splicing change Exon 9-included CCDC15 and exon 3-included RELL2 isoforms are oncogenic and tumor suppress