EDK
Editome Disease Knowledgebase
| miRNA ID | hsa-miR-142-3p | Editing sites | 1 |
|---|---|
| Species | Human |
| miRBase | NA |
| PMID | 29956457 |
| Description | MiR-142-3p accelerated migration and prolif- eration of cells via down-regulation of the STAU1. In summary, we established a pivotal LPS-ADAR2-miR-142-3p-STAU1 axis to provide a link between LPS and HSCR. |
| Disease | Hirschsprung’s disease; |
| Sequence |
| Enzyme | Editing Type | Editing-Level | Molecular Effect | Relationship | Correlation | Editing Effect | Phenotype | Disease | PMID |
|---|---|---|---|---|---|---|---|---|---|
| ADAR2 | U-to-C | Increase | miRNA expression change | Correlated | Positive | ADAR2 edits the pri-miR-142-3p and impairs cell proliferation and migration | Affect cell migration and proliferation | 29956457 |