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Human T-lymphotropic virus type 1 - HTLV-1

Virus Host Enzyme Edited Genes Phenotype Disease Details
Human T-lymphotropic virus type 1 Human APOBEC3G; APOBEC3A; APOBEC3B NA Antiviral Leukemia
  • Edited Gene Alias: NA
  • Editing Site: NA
  • Editing Type: G-to-A
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Negative
  • Description: Comparison of the A3-induced mutations from reporter cells and the patient-derived cell lines indicate that A3G but also other A3 members, possibly A3A and A3B, affect HTLV-1 in vivo. Taken together, our data indicate that HTLV-1 is a likely target for multiple A3 proteins.
  • PMID: 22457529