| Human Immunodeficiency virus type 2 |
Human |
APOBEC3A |
Inhibit viral replication |
Acquired immune deficiency syndrome (AIDS) |
|
- Correlation: Negative
- Description: This interaction led to a reduction of the steady-state protein level of A3A. A single- point mutation in Vpx (H82A) abrogated binding to A3A and single-round infection of monocytes by HIV-1.
- PMID: 20178977
|
| Human Immunodeficiency virus type 2 |
Human |
APOBEC3G |
Antiviral |
Acquired immune deficiency syndrome (AIDS) |
|
- Correlation: Negative
- Description: Polymorphism L71R of host restriction factors APOBEC3G, conferred resistance to Vif-mediated ubiquitin degradation, strongly suggesting that L71R might play an important role in antiviral defense mechanisms
- PMID: 30859472
|
EDK
Editome Disease Knowledgebase