Virus - EDK - BIG Data Center

Abbr: HPV16
Classification: ssRNA-RT
Protein Sequence: cell cycle modulating protein E1^E4; replication protein E1; regulatory protein E2; transforming protein E5; minor capsid protein L2; major capsid protein L1; transforming protein E6; protein E6*; transforming protein E7
Summary: Co-expression of A3A or A3C reduced the infectivity of PsV.

Virus	Host	Enzyme	Phenotype	Disease	Details
Human T-cell leukemia virus type 1	Human	ADAR1-p150	Enhance viral infection	Acquired immune deficiency syndrome (AIDS)
Correlation: Positive Description: ADAR1 enhances HTLV-1 and HTLV-2 infection in T-lymphocytes and that this proviral effect is independent from its editing activity. ADAR1 expression suppresses IFN-α inhibitory effect on HTLV-1 and HTLV-2 and acts through the repression of PKR phosphorylation. PMID: 25389016

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