Virus - EDK - BIG Data Center

Abbr: HPV16
Classification: dsDNA
Protein Sequence: cell cycle modulating protein E1^E4; replication protein E1; regulatory protein E2; transforming protein E5; minor capsid protein L2; major capsid protein L1; transforming protein E6; protein E6*; transforming protein E7
Summary: Co-expression of A3A or A3C reduced the infectivity of PsV.

Virus	Host	Enzyme	Phenotype	Disease	Details
Human papillomavirus 16	Human	APOBEC3	Co-expression of the editing enzyme reduced t	Virus infected disease
Correlation: Negative Description: APOBEC3 (A3) proteins were reported to hypermutate the genome of human papillomavirus 16 (HPV16), co-expression of A3A or A3C in 293FT cells greatly reduced the infectivity of PsV. PMID: 25576866

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