EDK Editome Disease Knowledgebase

  1. Home
  2. Editing Dependent Virus
  3. Sendai Virus

Sendai Virus - SeV

Virus Host Enzyme Edited Genes Phenotype Disease Details
Sendai Virus Human NA Phosphoprotein gene Produce new protein Virus infected disease
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G-to-U
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: Recoding
  • Correlation: NA
  • Description: The P gene also directs synthesis ofaccessory mRNAs for the V protein by inserting a pseudotemplated G residue at a specific editing site.
  • PMID: 12202220
Sendai Virus Human NA Phosphoprotein gene Produce new protein Virus infected disease
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: Recoding
  • Correlation: NA
  • Description: When the underlined AC of the SeV sequence was replaced by the UU found in bPIV3, the editing phenotype from both the minigenome and the recombinant virus resembled that found in natural bPIV3 infections
  • PMID: 9847338
Sendai virus Human NA P/C-gene Produce new protein Virus infected disease
  • Edited Gene Alias: NA
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Negative
  • Description: A Sendai virus P-gene mRNA with the predicted single-G insertion is present in infected cells and that this mRNA can be translated into a Cys-richV protein.Moreover, the activity that modifies the mRNA by G insertion appears to be coded for by the virus and to act during mRNA synthesis.
  • PMID: 1688384
Sendai virus Human NA Phosphoprotein (P) gene Antiviral Virus infected disease
  • Edited Gene Alias: P gene
  • Editing Site: NA
  • Editing Type: G insertion
  • Amino Acid Change: NA
  • Editing Level: Present
  • Molecular Consequence: NA
  • Correlation: Negative
  • Description: Sendai virus (SeV) and bovine parainfluenza virus type 3 (bPIV3) are closely related viruses, but SeV edits its P gene mRNA with the insertion of a single G residue (at approximately 50% frequency) within the sequence 5' A6G3, whereas bPIV3 inserts 1 to approximately 6 Gs at roughly equal frequency within the sequence 5' A6G4.
  • PMID: 7957115