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Human papillomaviruses type 11 - HPV

Virus Host Enzyme Edited Genes Phenotype Disease Details
Human papillomaviruses type 11 Human APOBEC3A hEP6 Antiviral Condyloma acuminatum
  • Edited Gene Alias: NA
  • Editing Site: NA
  • Editing Type: G-to-A; C-to-U
  • Amino Acid Change: NA
  • Editing Level: Increase
  • Molecular Consequence: Repressed viral gene expression
  • Correlation: Negative
  • Description: Enhanced A3A induced S-phase arrest, G > A/C > T mutations and obvious reduction of E6 mRNA expression. A3A/A3B mRNA expression was up-regulated at 6 h and 12 h and obvious A3A staining existed throughout HPV11.HaCaT cells after rhIFN-ω treatment. RhIFN-ω could also inhibit mRNA expression of HPV11 E6 significantly.
  • PMID: 29100527