EpiCancer
Epitranscriptomics in Cancers

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Regulation network in pan-cancer is built based on m6A regulator genes and their upstream regulation factors: miRNA, DNA methylation, and transcription factor (only shown in table version).

Regulators:

* Multiple selected is support

Created with Highcharts 9.0.1Chart context menuMETTL14​METTL14cg00604539​cg00604539cg01729388​cg01729388cg07243656​cg07243656cg20805999​cg20805999cg25149510​cg25149510hsa-miR-1307-3p​hsa-miR-1307-3pFTO​FTOhsa-miR-130a-5p​hsa-miR-130a-5phsa-miR-135a-5p​hsa-miR-135a-5phsa-miR-135b-5p​hsa-miR-135b-5phsa-miR-150-5p​hsa-miR-150-5phsa-miR-151a-3p​hsa-miR-151a-3phsa-miR-155-5p​hsa-miR-155-5phsa-miR-181a-5p​hsa-miR-181a-5phsa-miR-181b-5p​hsa-miR-181b-5phsa-miR-181c-5p​hsa-miR-181c-5phsa-miR-181d-5p​hsa-miR-181d-5phsa-miR-186-5p​hsa-miR-186-5phsa-miR-192-5p​hsa-miR-192-5phsa-miR-204-5p​hsa-miR-204-5phsa-miR-21-5p​hsa-miR-21-5phsa-miR-215-5p​hsa-miR-215-5phsa-miR-219a-5p​hsa-miR-219a-5phsa-miR-23a-3p​hsa-miR-23a-3phsa-miR-23a-5p​hsa-miR-23a-5phsa-miR-23c​hsa-miR-23chsa-miR-30a-5p​hsa-miR-30a-5phsa-miR-30b-3p​hsa-miR-30b-3phsa-miR-30b-5p​hsa-miR-30b-5phsa-miR-30c-1-3p​hsa-miR-30c-1-3phsa-miR-30c-2-3p​hsa-miR-30c-2-3phsa-miR-30c-5p​hsa-miR-30c-5phsa-miR-30d-5p​hsa-miR-30d-5phsa-miR-30e-5p​hsa-miR-30e-5phsa-miR-31-5p​hsa-miR-31-5phsa-miR-33a-5p​hsa-miR-33a-5phsa-miR-33b-5p​hsa-miR-33b-5phsa-miR-340-5p​hsa-miR-340-5phsa-miR-34c-3p​hsa-miR-34c-3phsa-miR-3913-5p​hsa-miR-3913-5phsa-miR-455-3p​hsa-miR-455-3phsa-miR-485-3p​hsa-miR-485-3phsa-miR-495-3p​hsa-miR-495-3phsa-miR-590-5p​hsa-miR-590-5pMETTL14​cg00604539METTL14​cg00604539METTL14​cg00604539METTL14​cg00604539METTL14​cg01729388METTL14​cg01729388METTL14​cg01729388METTL14​cg01729388METTL14​cg07243656METTL14​cg20805999METTL14​cg20805999METTL14​cg20805999METTL14​cg20805999METTL14​cg20805999METTL14​cg20805999METTL14​cg20805999METTL14​cg25149510METTL14​cg25149510METTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pMETTL14​hsa-miR-1307-3pFTO​hsa-miR-130a-5pFTO​hsa-miR-135a-5pFTO​hsa-miR-135b-5pFTO​hsa-miR-135b-5pFTO​hsa-miR-135b-5pFTO​hsa-miR-150-5pFTO​hsa-miR-151a-3pFTO​hsa-miR-151a-3pFTO​hsa-miR-151a-3pFTO​hsa-miR-155-5pFTO​hsa-miR-155-5pFTO​hsa-miR-155-5pFTO​hsa-miR-181a-5pFTO​hsa-miR-181a-5pFTO​hsa-miR-181a-5pFTO​hsa-miR-181b-5pFTO​hsa-miR-181b-5pFTO​hsa-miR-181b-5pFTO​hsa-miR-181c-5pFTO​hsa-miR-181c-5pFTO​hsa-miR-181d-5pFTO​hsa-miR-181d-5pFTO​hsa-miR-186-5pFTO​hsa-miR-186-5pFTO​hsa-miR-186-5pFTO​hsa-miR-192-5pFTO​hsa-miR-192-5pFTO​hsa-miR-204-5pFTO​hsa-miR-21-5pFTO​hsa-miR-21-5pFTO​hsa-miR-21-5pFTO​hsa-miR-21-5pFTO​hsa-miR-21-5pFTO​hsa-miR-21-5pFTO​hsa-miR-215-5pFTO​hsa-miR-219a-5pFTO​hsa-miR-23a-3pMETTL14​hsa-miR-23a-5pFTO​hsa-miR-23cFTO​hsa-miR-30a-5pFTO​hsa-miR-30b-3pFTO​hsa-miR-30b-3pMETTL14​hsa-miR-30b-3pMETTL14​hsa-miR-30b-3pFTO​hsa-miR-30b-3pFTO​hsa-miR-30b-5pFTO​hsa-miR-30b-5pFTO​hsa-miR-30b-5pFTO​hsa-miR-30c-1-3pFTO​hsa-miR-30c-2-3pMETTL14​hsa-miR-30c-2-3pFTO​hsa-miR-30c-5pFTO​hsa-miR-30c-5pFTO​hsa-miR-30d-5pFTO​hsa-miR-30d-5pFTO​hsa-miR-30d-5pFTO​hsa-miR-30d-5pFTO​hsa-miR-30d-5pFTO​hsa-miR-30e-5pFTO​hsa-miR-31-5pFTO​hsa-miR-31-5pFTO​hsa-miR-31-5pFTO​hsa-miR-33a-5pFTO​hsa-miR-33a-5pFTO​hsa-miR-33b-5pFTO​hsa-miR-33b-5pFTO​hsa-miR-33b-5pFTO​hsa-miR-340-5pMETTL14​hsa-miR-34c-3pMETTL14​hsa-miR-3913-5pFTO​hsa-miR-3913-5pFTO​hsa-miR-3913-5pMETTL14​hsa-miR-3913-5pMETTL14​hsa-miR-3913-5pFTO​hsa-miR-3913-5pMETTL14​hsa-miR-455-3pFTO​hsa-miR-485-3pFTO​hsa-miR-485-3pFTO​hsa-miR-485-3pFTO​hsa-miR-495-3pFTO​hsa-miR-495-3pFTO​hsa-miR-590-5pFTO​hsa-miR-590-5pFTO​hsa-miR-590-5pFTO​hsa-miR-590-5pregulatorsmiRNAsDNA methylation probes

miRNA sites

RegulatormiRNATCGA CancerCorrelation (normal)P Value (normal)Correlation (tumor)P Value (tumor)logFC of miRNAlogFC of regulator
FTOhsa-miR-130a-5pUCEC-0.49310.016816-0.1110.1570770.903-1.0442
FTOhsa-miR-135a-5pPRAD-0.24250.086381-0.323800.2195-0.5001
FTOhsa-miR-135b-5pLIHC-0.32240.0238460.04720.440531.9715-0.1091
FTOhsa-miR-135b-5pTHCA0.13920.301879-0.22350.0000010.2039-0.378
FTOhsa-miR-135b-5pUCEC-0.55730.005732-0.11070.148213.3372-1.0442
FTOhsa-miR-150-5pBRCA-0.31680.005966-0.05240.1532420.1405-0.9731
FTOhsa-miR-151a-3pBRCA0.05380.648911-0.16270.0000080.5709-0.9731
FTOhsa-miR-151a-3pLIHC0.41160.002983-0.19780.0001430.5414-0.1091
FTOhsa-miR-151a-3pPRAD-0.38830.0048640.270600.186-0.5001
FTOhsa-miR-155-5pBRCA0.07860.505825-0.1650.0000061.4505-0.9731
Note: LogFC is abbr. of Log(Fold Change of expression in tumor samples versus control samples,2).
Showing 1 to 10 of 92 entries

DNA methylation probes

RegulatorDNA methylation probeTCGA CancerCorrelation (normal)P Value (normal)Correlation (tumor)P Value (tumor)DeltaBetalogFC of regulator
METTL14cg00604539BRCA0.17920.140644-0.188900.0046-0.3413
METTL14cg00604539COAD0.17890.463554-0.12980.0316710.1449-0.2943
METTL14cg00604539HNSC0.09020.705213-0.16270.0002080.1675-0.0836
METTL14cg00604539KIRP0.03560.871984-0.22970.0001290.0982-0.5659
METTL14cg01729388KIRP-0.11070.615165-0.1560.0098520.0037-0.5659
METTL14cg01729388LIHC0.15910.320553-0.17070.0010080.1637-0.4492
METTL14cg01729388LUSC0.09520.822505-0.10980.0359220.0094-0.4046
METTL14cg01729388UCEC-0.33220.112773-0.22620.0029350.1917-0.7181
METTL14cg07243656LUSC-0.07140.866526-0.14480.0055680.0046-0.4046
METTL14cg20805999BRCA0.10530.389025-0.14420.0000620.0522-0.3413
Note: LogFC is abbr. of Log(Fold Change of expression in tumor samples versus control samples,2).
Showing 1 to 10 of 18 entries

Transcription factors