PRJNA681017: RNA sequence of gastric cancer with malignant ascites [RNA-seq]

Summary: Gastric cancer is one of the leading causes of cancer mortality worldwide, and peritoneal metastasis is a hallmark of incurable advanced gastric cancer. The identification of molecular vulnerability for such conditions is imperative to improve the prognosis of gastric cancer. Here, we comprehensively analysed cancer cells purified from malignant ascitic fluid samples and their corresponding cell lines from 98 patients, through whole-genome sequencing, whole transcriptome sequencing, methylation analyses, and genome-wide enhancer analyses.

Overall Design: Transcript analyses of purified tumour cells and cell lines of gastric cancer with malignant ascites.