HemAtlas
Mapping developmental hematopoiesis across stages, species and models

HemSC00000083

Dataset Information

Omics:
Single cell RNA-seq
Omics Detail:
10x Genomics
Species:
Human
Organ:
Bone marrow
Cell Number:
82742
Gene Number:
28659
Genome Reference:
GRCh38
Data Normalization:
SCT
Sequencing Platform:
10x Genomics
Cell Sorting Strategies:
an enrichment strategy that would capture hematopoietic cells, rare hematopoietic stem and progenitor cells (HSPCs), and non-hematopoietic microenvironmental cells. The three populations were pooled in a ratio favoring representation of rare HSPCs and non-hematopoietic cells and then subjected to scRNA-seq

Publication

Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging.

Bandyopadhyay S, Duffy MP, Ahn KJ, Sussman JH, Pang M, Smith D, Duncan G, Zhang I, Huang J, Lin Y, Xiong B, Imtiaz T, Chen CH, Thadi A, Chen C, Xu J, Reichart M, Martinez Z, Diorio C, Chen C, Pillai V, Snaith O, Oldridge D, Bhattacharyya S, Maillard I, Carroll M, Nelson C, Qin L, Tan K.
Volume:187 Issue:12 Cell | 2024-05-06 | [38714197]

Visualization

Annotation

Gene Expression (Feature plot)

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Gene Expression (Violin plot)

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Gene Expression (Dot plot)

Differentially Expressed Genes

Species Dataset Gene P.value logFC adj.P.val Stage Cell type Cluster

GO Enrichment

Cell Interaction

Species Stage Dataset Source Target Communication probability P value Ligand Receptor Interact Name