HemAtlas
Mapping developmental hematopoiesis across stages, species and models

HemSC01000087

Dataset Information

Omics:
Single cell RNA-seq
Omics Detail:
10x Genomics
Species:
Zebrafish
Organ:
AGM (aorta-gonad-mesonephros)
CHT (caudal hematopoietic tissue)
KM (kidney marrow)
Cell Number:
62954
Gene Number:
31799
Genome Reference:
GRCz11
Data Normalization:
SCT
Sequencing Platform:
Integrated data
Cell Sorting Strategies:
Integrated data

Publication

Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity.

Xia J, Liu M, Zhu C, Liu S, Ai L, Ma D, Zhu P, Wang L, Liu F.
Volume: Issue: Cell research | 2023-04-04 | [37016019]

The N-glycome regulates the endothelial-to-hematopoietic transition.

Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S.
Volume:370 Issue:6521 Science (New York, N.Y.) | 2020-12-03 | [33273096]

A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis.

Xue Y, Liu D, Cui G, Ding Y, Ai D, Gao S, Zhang Y, Suo S, Wang X, Lv P, Zhou C, Li Y, Chen X, Peng G, Jing N, Han JJ, Liu F.
Volume:27 Issue:5 Cell reports | 2019-04-01 | [31042481]

A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish.

Xia J, Kang Z, Xue Y, Ding Y, Gao S, Zhang Y, Lv P, Wang X, Ma D, Wang L, Han JJ, Liu F.
Volume:118 Issue:14 Proceedings of the National Academy of Sciences of the United States of America | 2021-04-01 | [33785593]

Single-cell RNA sequencing unveils the hidden powers of zebrafish kidney for generating both hematopoiesis and adaptive antiviral immunity.

Hu C, Zhang N, Hong Y, Tie R, Fan D, Lin A, Chen Y, Xiang LX, Shao JZ.
Volume:13 Issue: eLife | 2024-03-18 | [38497789]

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.

Tang Q, Iyer S, Lobbardi R, Moore JC, Chen H, Lareau C, Hebert C, Shaw ML, Neftel C, Suva ML, Ceol CJ, Bernards A, Aryee M, Pinello L, Drummond IA, Langenau DM.
Volume:214 Issue:10 The Journal of experimental medicine | 2017-09-06 | [28878000]

Visualization

Annotation

Gene Expression (Feature plot)

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Gene Expression (Violin plot)

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Gene Expression (Dot plot)

Cell Number Across Stages