Disease Description: A rare clotting disorder primarily of American cocker spaniels. An autosomal trait (affects both sexes).
Inherit Mode: autosomal-recessive
Disease Symptom: Factor X deficiency is very dangerous, even fatal in newborn and young puppies, sometimes leading to severe internal bleeding. Adult dogs are not so severely affected, usually appearing healthy and displaying the symptoms of bleeding disorder during surgery or injuries with mild episodes of prolonged bleeding.
Disease Cause: -
Disease Diagnose: -
Treat Method: -
Breeder Advice: -
Disease Description Source: Link
| Disease Name | Other Name | Mode of inheritance | Link ID | Possible OMIM ID | Gene |
|---|---|---|---|---|---|
| Factor X deficiency | - | - | - |
| iDog Breed Number | Breed Name | Personality | Height | Weight | Breed Source |
|---|---|---|---|---|---|
| CB78 | Cocker Spaniel | Happy, smart, gentle | 36.8-39.4 cm (male), 34.3-36.8 cm (female) | 11.3-13.6 kg (male), 9.1-11.3 kg (female) | |
| CB98 | English Toy Spaniel | Affectionate, Alert, Merry | 22.9-25.4 cm | 3.6-6.4 kg | England |
| CB177 | Parson Russell Terrier | Bold, friendly, athletic, and clever | 35.6 cm (male), 33 cm (female) | 5.9-7.7 kg | United Kingdom (England) |
| 2016 |
Heuss,J.,Weatherton,L.: :
A case of factor X deficiency in a Chihuahua dog. Can Vet J 57:865-8, 2016. Pubmed reference: 27493287 . |
| 1988 |
Fogh,J.M.,Fogh,I.T.: :
Inherited coagulation disorders. Vet Clin North Am Small Anim Pract 18:231-43, 1988. Pubmed reference: 3282382 . |
| 1978 |
Takeda,Y.,Arai,H.: :
Effects of heparin, typhoid vaccine and thrombophlebitis on factor X metabolism in the dog. Thromb Haemost 40:118-27, 1978. Pubmed reference: 725842 . |
| 1977 |
Arai,H.,Takeda,Y.: :
Physicochemical and immunological properties of canine factor X and activated factor X. Thromb Res 11:357-64, 1977. Pubmed reference: 411192 . |
| 1977 |
Arai,H.,Takeda,Y.: :
Properties and radioimmunoassay of canine factor X. Thromb Res 11:57-66, 1977. Pubmed reference: 888119 . |
| 1973 |
Dodds,W.J.: :
Canine factor X (Stuart-Prower factor) deficiency. J Lab Clin Med 82:560-6, 1973. Pubmed reference: 4755433 . |