The detail information of Thyroiditis
Basic Information

Another Name: Hashimoto's disease

Disease Description: An autoimmune inflammatory disease of the thyroid gland (See #166, and 192.).

Inherit Mode: -

Disease Symptom: Thyroiditis or Hashimoto's disease will manifest through symptoms that are typical for dogs with a low thyroid gland function. Watch out for symptoms such as:Reduced metabolism and weight gain, even if the dog eats the same amount of food or even less than usual;Dry mouth and mucous membranes;Dry coat and skin;Hair loss;Lethargy;Elevated fever;Swelling of the joints.The dog may not present any symptoms when the disease debuts, but as it advances, he may display more visible symptoms.

Disease Cause: Thyroiditis is an immune system mediated disease and the exact causes of this condition are not known. There may be certain factors that can affect the immune system and determine it to attack its own cells, resulting in hypothyroidism. Some triggering factors may include:Exposure to toxins such as cigarette smoke or poisonous metals;Side effects of certain drugs;Administration of vaccines.Autoimmune thyroiditis is among the most common causes of hypothyroidism in canines.

Disease Diagnose: Hashimoto's disease can be diagnosed by performing a few tests that will assess the function of the thyroid gland. The levels of TSH, T3 and T4 will be measured. If the dog has hypothyroidism, these will have lower values than the normal for the dog’s breed.To detect thyroiditis, the vet will have to perform certain tests to assess the activity of the immune system.

Treat Method: The treatment for Hashimoto's disease will have to address the 2 main problems:The thyroid function;The immune system function

Breeder Advice: -

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Thyroiditis - - - -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB4 Akita Dignified, courageous, and profoundly loyal to their humans 66-71.1 cm (male), 61-66 cm (female) 45.4-59 kg (male), 31.8-45.4 kg (female) Japan
CB25 Bearded Collie Bouncy, charismatic, friendly; smart, but also stubborn and independent 53.3-55.9 cm (male), 50.8-53.3 cm (female) 20.4-24.9 kg United Kingdom (Scotland)
CB46 Boston Terrier Friendly, bright, amusing, and adaptable. 38.1-43.2 cm 4.5-11.3 kg United States
CB49 Boykin Spaniel Friendly, eager, trainable, lovable 39.4-45.7 cm (male), 35.6-41.9 cm (female) 13.6-18.1 kg (male), 11.3-15.9 kg (female) United States
CB76 Cirneco dell'Etna Affectionate, Friendly, Independent 18-19.5 inches (male), 16.5-18 inches (female) 22-26 pounds (male), 17-22 pounds (female) Italy
CB89 Dogo Argentino Loyal, trustworthy,courageous 61-68.6 cm (male), 59.7-66 cm (female) 36.3-45.4 kg Argentina
CB115 Irish Glen of Imaal Terrier Gentler, less excitable than most terriers, but still bold and spirited 31.8-35.6 cm 14.5-18.1 kg Ireland
CB117 Gordon Setter Bold, confident, and resolute afield; sweetly affectionate by the fireside 61-68.6 cm (male), 58.4-66 cm (female) 24.9-36.3 kg (male), 20.4-31.8 kg (female) United Kingdom (Scotland)
CB120 Great Pyrenees Calm, patient, smart; strong-willed yet affectionate 68.6-81.3 cm (male), 63.5-73.7 cm (female) 45.4 kg & up (male), 38.6 kg & up (female) France, Spain
CB156 Manchester Terrier Spirited, bright, keenly observant; dead loyal, in an independent terrier way 38.1-40.6 cm 5.4-10 kg (standard) United Kingdom (England)
CB167 Norfolk Terrier Alert, fearless, fun-loving, and more sociable than the usual terrier 22.9-25.4 cm 5-5.4 kg United Kingdom
CB175 Otterhound Even-Tempered, amiable, boisterous 68.6 cm (male), 61 cm (female) 52.2 kg (male), 36.3 kg (female) United Kingdom (England)
CB206 Russell Terrier Alert, lively, inquisitive, and friendly 25.4-30.5 cm 4.1-6.8 kg United Kingdom (England)
CB217 Japanese Shiba Inu Alert, active, and attentive 35.6-43.2 cm (male), 33-40.6 cm (female) 8.2-10.9 kg (male), 6.8-9.1 kg (female) Japan
CB223 Sloughi A true sighthound: noble, loyal to loved ones, regally aloof with strangers 66-73.7 cm (male), 61-68.6 cm (female) 15.9-22.7 kg Morocco
CB242 Tibetan Mastiff Mellow and calm around the house; devoted to family, reserved and territorial with strangers. 66-76.2 cm (male), 61-71.1 cm (female) 45.4-72.6 kg (male), 34-54.4 kg (female) Tibet
References
2010 Wilbe,M.,Sundberg,K.,Hansen,IR.,Strandberg,E.,Nachreiner,RF.,Hedhammar,A.,Kennedy,LJ.,Andersson,G.,Bjornerfeldt,S.: :
Increased genetic risk or protection for canine autoimmune lymphocytic thyroiditis in Giant Schnauzers depends on DLA class II genotype. Tissue Antigens 75:712-9, 2010.
Pubmed reference: 20210920 . DOI: 10.1111/j.1399-0039.2010.01449.x .
1999 Dixon,R.M.,Murray,M.: :
UK screening programme for canine autoimmune thyroiditis Veterinary Record 145:472, 1999.
Pubmed reference: 10576290 .
1997 Vajner,L.,Vortel,V.,Brejcha,A.: :
Lymphocytic thyroiditis in Beagle dogs in a breeding colony - histological findings Veterinarni Medicina 42:43-49, 1997.
Pubmed reference: 9127579 .
1996 Benjamin,S.A.,Stephens,L.C.,Hamilton,B.F.,Saunders,W.J.,Lee,A.C.,Angleton,G.M.,Mallinckrodt,C.H.: :
Associations between lymphocytic thyroiditis, hypothyroidism, and thyroid neoplasia in beagles Veterinary Pathology 33:486-494, 1996.
Pubmed reference: 8885174 .
1968 Musser,E.,Graham,W.R.: :
Familial occurrence of thyroiditis in purebred Beagles Laboratory Animal Care 18:58-68, 1968.
Pubmed reference: 4171024 .