The detail information of brachycephalic syndrome
Basic Information

Disease Description: Brachycephalic syndrome in dogs is when your dog has a shortened skull in comparison to other breeds. Effects of this condition can include breathing difficulties, difficulties with exercise, and overheating to name a few concerns, and is breed specific mostly.

Inherit Mode: Selection for exaggerated features has resulted in the respiratory difficulties in these breeds. For example breed standards for the English bulldog specify that the face should be very short, as should the distance between the tip of the nose and where it is set deep between the eyes. It is hardly surprising that this leaves little room for the structures involved in normal breathing.

Disease Symptom: Problems associated with this syndrome range in severity, with most brachycephalic dogs snuffling and snorting to some degree. Some will have no further difficulties, but many will have problems such as increasingly noisy breathing, coughing and gagging, fainting or collapsing episodes, and a decreased tolerance for exercise (ie. they tire easily). Over the long term, this also puts an increased strain on the heart. Some dogs, such as English bulldogs, may have frequent episodes of sleep-disordered breathing. Overheating is especially dangerous in these breeds, because increased panting (the normal mechanism for cooling in dogs) can cause further swelling and narrowing of the already constricted airways, which will increase your dog's anxiety. Excitement, exercise, or warm weather (and especially a combination of these factors) can trigger this vicious cycle. These dogs can also have gastrointestinal problems, because of difficulties coordinating swallowing when they are working so hard at breathing. This can result in vomiting ar gagging because of swallowing so much air, or aspiration pneumonia, because of breathing in saliva or food particles. All dogs of these breeds have an increased risk associated with sedation and anesthesia, for which your veterinarian will take extra precautions.

Disease Cause: -

Disease Diagnose: These problems are usually evident from a young age. If your dog has respiratory difficulties, your veterinarian may discuss this syndrome with you as part of a regular visit, or you may bring your dog in because of an episode such as collapsing after exercise. Because some changes in anatomy are common to all dogs of these breeds, diagnosis is really a question of the degree of abnormality. The overlong soft palate is best examined under general anesthesia, and so, because of the associated risks, your vet will most likely ask your permission in advance to surgically correct it at the same time if necessary. Neutering can often be performed at the same time.

Treat Method: Medical treatment (oxygen therapy, corticosteroids) can be used for short term relief of airway inflammation. Surgery is required where severe anatomic faults interfere with breathing. Most commonly this involves removal of some of the excess fleshy soft palate, and widening of air passages at the nostrils. It is important to keep your dog from becoming overweight, as this will worsen his or her respiratory difficulties in the long run.

Breeder Advice: This syndrome is directly related to the conformation or standards for these breeds. Although so common as to be accepted as normal for brachycephalics, BAOS causes serious physical problems and discomfort for individual dogs. Breed improvement by breeding away from the extremes of conformation that cause these problems, is a challenge for responsible breeders. Dogs with pronounced breathing difficulties or that have required surgery to correct airway obstruction, should not be used for breeding. These dogs should be neutered at the time surgical correction is performed.

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Brachycephaly - Multifactorial SMOC2 BMP3
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB46 Boston Terrier Friendly, bright, amusing, and adaptable. 38.1-43.2 cm 4.5-11.3 kg United States
CB58 English Bulldog Calm, courageous, and friendly; dignified but amusing. 35.6-38.1 cm 22.7 kg (male), 18.1 kg (female) United Kingdom (England)
CB73 Chinese Shar-Pei Steadfastly devoted to loved ones, but standoffish and lordly toward strangers 45.7-50.8 cm 20.4-27.2 kg China
CB106 French Bulldog Playful, smart, adaptable, and completely irresistible 27.9-33 cm under 12.7 kg United Kingdom (England), France
CB153 Lhasa Apso(Long-Haired Lhasa Dog) Smart, confident, complex; a family comedian, but regally aloof with strangers 25.4-27.9 cm (male), slightly smaller (female) 5.4-8.2 kg Tibet
CB178 Pekingese Affectionate, loyal, regal in manner 15.2-22.9 cm up to 6.4 kg China
CB196 Pug Even-tempered, charming, mischievous and loving 25.4-33 cm 6.4-8.2 kg China
CB218 Shih Tzu(Chrysanthemum Dog) Outgoing, affectionate, playful and charming 20.3-27.9 cm 4.1-7.3 kg China
CB234 Staffordshire Bull Terrier Brave, tenacious, a bit stubborn; but also gentle, playful, and clever 35.6-40.6 cm 12.7-17.2 kg (male), 10.9-15.4 kg (female) United Kingdom (England)
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