The detail information of Episodic falling
OMIA Basic Information
Possible human homologues (MIM numbers): -
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2012
Species-specific name: -
Species-specific symbol: -
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB67 | Cavalier King Charles Spaniel | 30.5-33 cm | 5.9-8.2 kg | United Kingdom (England) |
Associated Gene
| Symbol | Description | Species | Position | Other Links |
|---|---|---|---|---|
| BCAN | brevican | Canis lupus familiaris | Chr7 : 41193313 - 41176717 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2019 |
Lewis,T.W.,Mellersh,C.S.: :
Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test. PLoS One 14:e0209864, 2019. Pubmed reference: 30650096 . DOI: 10.1371/journal.pone.0209864 . |
| 2012 |
Forman,O.P.,Penderis,J.,Hartley,C.,Hayward,L.J.,Ricketts,S.L.,Mellersh,C.S.: :
Parallel Mapping and Simultaneous Sequencing Reveals Deletions in BCAN and FAM83H Associated with Discrete Inherited Disorders in a Domestic Dog Breed. PLoS Genet 8:e1002462, 2012. Pubmed reference: 22253609 . DOI: 10.1371/journal.pgen.1002462 . |
| 2012 |
Gill,J.L.,Tsai,K.L.,Krey,C.,Noorai,R.E.,Vanbellinghen,J.F.,Garosi,L.S.,Shelton,G.D.,Clark,L.A.,Harvey,R.J.: :
A canine BCAN microdeletion associated with episodic falling syndrome. Neurobiol Dis 45:130-6, 2012. Pubmed reference: 21821125 . DOI: 10.1016/j.nbd.2011.07.014 . |
| 1983 |
Herrtage,ME.,Palmer,AC.: :
Episodic falling in the cavalier King Charles spaniel. Vet Rec 112:458-9, 1983. Pubmed reference: 6868317 . |