The detail information of Glaucoma, primary closed-angle
OMIA Basic Information

Possible human homologues (MIM numbers): -

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB22 Basset Hound up to 38.1 cm 18.1-29.5 kg France
CB85 Dandie Dinmont Terrier 20.3-27.9 cm 8.2-10.9 kg United Kingdom (Scotland)
Associated Gene
Symbol Description Species Position Other Links
NEB nebulin Canis lupus familiaris Chr- : - - - Homologene, Ensembl, NCBI gene
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2019 Oliver,J.A.C.,Ricketts,S.L.,Kuehn,M.H.,Mellersh,C.S.: :
Primary closed angle glaucoma in the Basset Hound: Genetic investigations using genome-wide association and RNA sequencing strategies. Mol Vis 25:93-105, 2019.
Pubmed reference: 30820145 .
2017 Graham,K.L.,McCowan,C.,White,A.: :
Genetic and Biochemical Biomarkers in Canine Glaucoma. Vet Pathol 54:194-203, 2017.
Pubmed reference: 27681326 . DOI: 10.1177/0300985816666611 .
2015 Ahram,D.F.,Grozdanic,S.D.,Kecova,H.,Henkes,A.,Collin,R.W.,Kuehn,M.H.: :
Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds. PLoS One 10:e0126660, 2015.
Pubmed reference: 25938837 . DOI: 10.1371/journal.pone.0126660 .
2015 Komáromy,A.M.,Petersen-Jones,S.M.: :
Genetics of Canine Primary Glaucomas. Vet Clin North Am Small Anim Pract 45:1159-82, v, 2015.
Pubmed reference: 26277300 . DOI: 10.1016/j.cvsm.2015.06.003 .
2015 Pearl,R.,Gould,D.,Spiess,B.,Pearl,R.,Gould,D.,Spiess,B.: :
Progression of pectinate ligament dysplasia over time in two populations of Flat-Coated Retrievers. Vet Ophthalmol 18:6-12, 2015.
Pubmed reference: 24025050 . DOI: 10.1111/vop.12098 .
2015 Pizzirani,S.: :
Definition, Classification, and Pathophysiology of Canine Glaucoma. Vet Clin North Am Small Anim Pract 45:1127-57, v, 2015.
Pubmed reference: 26456751 . DOI: 10.1016/j.cvsm.2015.06.002 .
2014 Ahram,D.F.,Cook,A.C.,Kecova,H.,Grozdanic,S.D.,Kuehn,M.H.: :
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound. Mol Vis 20:497-510, 2014.
Pubmed reference: 24791135 .
2013 Ahonen,S.J.,Pietilä,E.,Mellersh,C.S.,Tiira,K.,Hansen,L.,Johnson,G.S.,Lohi,H.: :
Genome-wide association study identifies a novel canine glaucoma locus. PLoS One 8:e70903, 2013.
Pubmed reference: 23951034 . DOI: 10.1371/journal.pone.0070903 .