Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Dominant
Considered a defect: yes
Year key mutation first reported: 2001
Species-specific name: bob-tail, bob tail
Species-specific symbol: -
More detail information can see in
Symbol | Description | Species | Position | Other Links |
---|---|---|---|---|
T | T brachyury transcription factor | Canis lupus familiaris | Chr1 : 54369833 - 54360266 | Homologene, Ensembl, NCBI gene |
2009 |
Hytönen,M.K.,Grall,A.,Hédan,B.,Dréano,S.,Seguin,S.J.,Delattre,D.,Thomas,A.,Galibert,F.,Paulin,L.,Lohi,H.,Sainio,K.,André,C.: :
Ancestral T-box mutation is present in many, but not all, short-tailed dog breeds. J Hered 100:236-40, 2009. Pubmed reference: 18854372 . DOI: 10.1093/jhered/esn085 . |
2008 |
Indrebø,A.,Langeland,M.,Juul,H.M.,Skogmo,H.K.,Rengmark,A.H.,Lingaas,F.: :
A study of inherited short tail and taillessness in Pembroke Welsh corgi. J Small Anim Pract 49:220-4, 2008. Pubmed reference: 17850278 . DOI: 10.1111/j.1748-5827.2007.00435.x . |
2008 |
Jones,P.,Chase,K.,Martin,A.,Davern,P.,Ostrander,EA.,Lark,KG.: :
Single-nucleotide-polymorphism-based association mapping of dog stereotypes. Genetics 179:1033-44, 2008. Pubmed reference: 18505865 . DOI: 10.1534/genetics.108.087866 . |
2001 |
Haworth,K.,Putt,W.,Cattanach,B.,Breen,M.,Binns,M.,Lingaas,P.,Edwards,Y.H.: :
Canine homolog of the T-box transcription factor T; failure of the protein to bind to its DNA target leads to a short-tail phenotype Mammalian Genome 12:212-218, 2001. Pubmed reference: 11252170 . DOI: 10.1007/s003350010253 . |
1957 |
Pullig,T.: :
Brachyury in Cocker Spaniels Journal of Heredity 48:75-76, 1957. |
1934 |
Little,C.C.: :
Inheritance in Toy Griffons Journal of Heredity 25:198-201, 1934. |