Somatolactin stimulates in vitro gonadal steroidogenesis in coho salmon, Oncorhynchus kisutch.

J V Planas, P Swanson, M Rand-Weaver, W W Dickhoff
Author Information
  1. J V Planas: School of Fisheries HF-15, University of Washington, Seattle 98195.

Abstract

Somatolactin (SL), a newly discovered pituitary hormone of the teleost pars intermedia, is structurally similar to prolactin and growth hormone. The function(s) of SL are not yet established, although evidence suggests that it may play a role in reproduction. Possible steroidogenic activity of coho salmon SL was tested and compared with gonadotropin I (GTH I) in incubations of ovarian follicles or testicular fragments. SL stimulated production of 11-ketotestosterone and testosterone by testicular fragments, and production of estradiol by ovarian follicles in a concentration-dependent manner. However, the steroidogenic activity of SL was considerably less than that of GTH I. These results suggest that SL may play a role in regulation of gonadal function in salmon.

MeSH Term

Animals
Dose-Response Relationship, Drug
Estradiol
Female
Fish Proteins
Glycoproteins
Gonadotropins, Pituitary
In Vitro Techniques
Male
Ovarian Follicle
Pituitary Hormones
Salmon
Testis
Testosterone

Chemicals

Fish Proteins
Glycoproteins
Gonadotropins, Pituitary
Pituitary Hormones
somatolactin protein, fish
gonadotropin- pituitary, beta-subunit I, salmon
Testosterone
Estradiol
11-ketotestosterone

Word Cloud

Created with Highcharts 10.0.0SLsalmonSomatolactinhormonefunctionmayplayrolesteroidogenicactivitycohoGTHovarianfolliclestesticularfragmentsproductiongonadalnewlydiscoveredpituitaryteleostparsintermediastructurallysimilarprolactingrowthsyetestablishedalthoughevidencesuggestsreproductionPossibletestedcomparedgonadotropinincubationsstimulated11-ketotestosteronetestosteroneestradiolconcentration-dependentmannerHoweverconsiderablylessresultssuggestregulationstimulatesvitrosteroidogenesisOncorhynchuskisutch

Similar Articles

Cited By (15)