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European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
1990;247 (4): 252-5.

Vimentin as a marker of myoepithelial cells in salivary gland tumors.

V C de Araújo, N S de Araújo
Author Information
  1. V C de Araújo: Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil.
PMID: 2165413 DOI: 10.1007/BF00178997

Abstract

Thirty-six salivary gland tumors from the Surgical Oral Pathology Service of the University of São Paulo, School of Dentistry, have been examined by immunostaining, using commercially available antibody to vimentin. The samples analyzed included tumors in which the participation of myoepithelial cells as a tumoral component has been postulated, i.e., pleomorphic adenoma, myoepithelioma, epithelial-myoepithelial adenoma, monomorphic adenoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, and polymorphous low-grade adenocarcinoma. Our results strongly support the view that vimentin is one of the earliest indicators of neoplastic myoepithelial differentiation.

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MeSH Term

Adenocarcinoma
Adenoma
Adenoma, Pleomorphic
Biomarkers, Tumor
Carcinoma, Adenoid Cystic
Humans
Immunoenzyme Techniques
Myoepithelioma
Salivary Gland Neoplasms
Vimentin

Chemicals

Biomarkers, Tumor
Vimentin
Journal Article Research Support, Non-U.S. Gov't

Word Cloud

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