Sjögren's syndrome: association with type-1 diabetes mellitus.

A Binder, P J Maddison, P Skinner, A Kurtz, D A Isenberg

Author Information

A Binder: Bloomsbury Rheumatology Unit, University College, London.

PMID: 2590806 DOI: 10.1093/rheumatology/28.6.518

This study of 102 unselected type-1 diabetic patients has shown that sicca symptoms affect 55% of the patients, although sometimes only during hyperglycaemic phases. While these symptoms might be attributable to the diabetes, the frequency of antinuclear antibodies in those suspected of having Sjögren's (25% by HEp-2) and particularly anti-Ro antibodies (32% by ELISA) reinforces the suspicion that Sjögren's syndrome may underlie their presence.

Adolescent

Adult

Antibodies, Antinuclear

Diabetes Mellitus, Type 1

Female

Humans

Hyperglycemia

Male

Middle Aged

Prevalence

Sjogren's Syndrome

Antibodies, Antinuclear

Journal Article

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