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The Journal of antibiotics
Jan, 1988;41 (1): 45-52.

New aureolic acid antibiotics. I. Screening, isolation, characterization and biological properties.

M Koenuma, N Uchida, K Yamaguchi, Y Kawamura, K Matsumoto
Author Information
  1. M Koenuma: Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
PMID: 3346192 DOI: 10.7164/antibiotics.41.45

Abstract

A new antibiotic complex was isolated from the fermentation broth of Streptomyces aburaviensis PA-39856. The individual factors, demethylolivomycins A, B and demethylchromomycins A2, A3 were separated and purified by preparative HLC. These antibiotics possess high activities against Gram-positive bacteria and P388 leukemia in mice.

MeSH Term

Antibiotics, Antineoplastic
Chemical Phenomena
Chemistry
Magnetic Resonance Spectroscopy
Streptomyces

Chemicals

Antibiotics, Antineoplastic
Journal Article

Word Cloud

Created with Highcharts 10.0.0antibioticsnewantibioticcomplexisolatedfermentationbrothStreptomycesaburaviensisPA-39856individualfactorsdemethylolivomycinsBdemethylchromomycinsA2A3separatedpurifiedpreparativeHLCpossesshighactivitiesGram-positivebacteriaP388leukemiamiceNewaureolicacidScreeningisolationcharacterizationbiologicalproperties

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